Betamethasone Acetate White Powders For Anti Inflammatory CAS NO.987-24-6

CAS 987-24-6 White Powde Betamethasone Acetate for Skin Nature From Factory

Quick details:

Product name: Betamethasone
CAS No.: 378-44-9
Assay: 99%
Molecular Formula: C22H29FO5
Molecular Weight: 392.461
Appearance: White or almost white crystalline powder
Specification: USP/BP
Min. Order quantity: 10g

Description:

Betamethasone, dexamethasone of isomers, the role and purpose with dexamethasone acetate, the sodium and water retention effect and dose than the latter is small. Glucose metabolism and anti-inflammatory effect than hydrocortisone strong as hydrocortisone 15 times, but the effect of sodium retention hydrocortisone hundred times more, in primary adrenal hypofunction in with glucocorticoid steroid replacement therapy used together. Also suitable for low renin and low aldosterone syndrome, autonomic neuropathy induced orthostatic hypotension. Because of the goods taken orally is prone to cause edema, more topically applying topical treatment for seborrheic eczema, contact dermatitis, anal, genital itching embolism. Mainly used for allergic and autoimmune inflammatory diseases. It is used for activities rheumatism, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, but also for the comprehensive treatment of certain infections.

Applications:

Corticosteroid is any of the synthetic or naturally occurring 21-carbon steroid structure substances with four fused rings and vary functional branches attached to the ring system. Cholesterol and steroid hormones have this carbon skeleton. The term steroid refers to these three groups that contain a hydrogenated cyclopentano perhydro phenanthrene ring system. In restricted context for medical usage by non-endocrinologists, it refers to corticosteroids. Natural corticosteroids are elaborated by the adrenal cortex in response to physiological carbohydrate metabolism. According to their predominant biologic activity, they are divided into two major groups: glucocorticoid and mineralocorticoid. Glucocorticoid's chief function is to regulate carbohydrate, lipid, and protein metabolism and inhibit the release of ACTH (adrenocorticotropic hormone). Glucocorticoids also affect muscle tone and the microcirculation, participate in the maintenance of arterial blood pressure, increase gastric secretion, alter connective tissue response to injury, impede cartilage production, inhibit inflammatory, allergic, and immunologic responses, invoke shrinkage of lymphatic tissue, reduce the number of circulating lymphocytes, and affect the functions of the central nervous system. In humans, the most important ones are cortisol, cortisone, and corticosterone. Mineralocorticoids, uniuqely aldosterone in human, regulate the balance of water and promote retention of sodium, loss of potassium. Aldosterone plays a role also in promoting tissue repair. Spironolactone is the aldosterone antagonist called potassium-sparing diuretic used in the treatment of hypertension. Corticosteroids are used in clinically for hormonal replacement therapy, for suppression of ACTH, as antineoplastic, antiallergic, and anti-inflammatory agents, and to suppress immune responses.

Usage:

Betamethasone Acetate is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby, Crohn disease, cancers such as leukemia, and along with fludrocortisone for adrenocortical insufficiency, among others.

Attention :

Allergic to the goods and other steroid.The following diseases generally are not special circumstances should be weighed against the use, but should pay attention to disease progression may be: a serious mental illness (past or present), and epilepsy, active peptic ulcer disease, recent gastrointestinal anastomosis, fracture, wound healing period , corneal ulcers, adrenal cortex hyperactivity disorder, hypertension, diabetes, pregnant women, antibiotics can not control the infection, such as chicken pox, measles, fungal infections, heavier osteoporosis.

Function&usage:

1.It is stronger than cortisol about methoxyflavone sugar metabolism and anti-inflammatory , amost 15 times stronger than cortisol.
2.For hydrocortisone sodium retention role,it is more than one hundred time stronger than cortisol.
3.In the primary adrenal cortical impairment of disease,it can be used for replacement therapy together with sugar corticosteroids.
4.It is also used for low renin and low aldosterone syndrome and plant nerve lesions orthostatic hypotension caused by etc.