- Product Details
Keywords
- 97240-79-4
- Topiramate
- Topamax
Quick Details
- ProName: Strong 99% Anticonvulsant Active Pharm...
- CasNo: 97240-79-4
- Molecular Formula: C12H21NO8S
- Appearance: White crystal
- Application: Pharmaceutical Ingredients
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 20000 Kilogram/Day
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 100 Gram
Superiority
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
5. High quality & competitive price;
Details
Strong 99% Anticonvulsant Active Pharmaceutical Ingredients Topiramate CAS 97240-79-4
Topiramate-----------Quick Details
Topiramate Product Name: Topiramate
Topiramate CAS: 97240-79-4
Topiramate MF: C12H21NO8S
Topiramate MW: 339.36
Topiramate EINECS: 200-659-6
Topiramate Product Categories: Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Topiramate Melting point : 125°C
Topiramate Storage temp. : 2-8°C
Topiramate Chemical Properties : White-to-Off-White Crystalline Powder
Topiramate Usage : anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor
Topiramate-----------Description
Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. In late 2012, topiramate was approved by the United States Food and Drug Administration (FDA) in combination with phentermine for weight loss. The drug had previously been used off-label for this purpose.
Topiramate was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of the Johnson & Johnson Corporation. This medication was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceutical.
Topiramate COA
Items |
Specifications |
Results |
Appearance | White to off-white powder, Freely soluble in dichloromethane | White powder, Freely soluble in dichloromethane |
Identification | Infared Absorption | Complies |
The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies | |
Specific rotation | Between -28.6°and -35.0°, measured at 20° | -32.8° |
Water | not more than 0.5% | 0.12% |
residue on ignition | not more than 0.2% | 0.11% |
Heavy metals | not more than 0.001% | complies |
related compounds by HPLC(Test1) | Fructose not more than 0.3% Compound A not more than 0.3% Other individual impurity not more than 0.1% Total impurities not more than 0.5% |
Fructose: 0.03% Compound A:0.04%individual impurity Total impurities: 0.07% |
Particle size | 90% less than 350 microns | complies |
Limit of sulfamate and sulfate | Sulfamate ion not more than 0.10% Sulfate ion not more than 0.10% | complies |
Residual Solvent | Methylene Chloride not more than 250μg/g | not detected |
Acetone not mor than 2500μg/g | ||
Isopropanol not more than 5000μg/g | ||
Ethanenitrile not more than 400μg/g | ||
n-hexane not more than 290μg/g | ||
Ethyl Acetate not more than 2500μg/g | ||
Pyridine not more than 100μg/g | ||
Assay | Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis | 99.80% |
Conclustion | The material complies with respect to USP35 |
Topiramate Medical uses
Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay.
Topiramate is also Food and Drug Administration (FDA) approved for, and most frequently prescribed for, the prevention of migraines. The drug is also used to treat migraines due to the effect it has on the blood vessels in the brain. It has been found to be increasingly effective for migraine sufferers with limited side effects .
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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Strong 99% Anticonvulsant Active Pharmaceutical Ingredients Topiramate CAS 97240-79-4