Products Categories

  • Mr.Bruce Li
    Tel: +86-027-83214688

  • Ms.Linda Yang
    sales
    Tel: +8618874586545

  • Ms.Niyoe Tan
    sales
    Tel: 17720330692

  • Ms.rany
    Tel: +8618627068784

  • Ms.Yuki
    Tel: +8618871152735

  • Mobile:
  • Tel:+86-027-83214688
  • Fax:02783214688
  • Province/state:Hubei
  • City:Wuhan
  • Street:666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province, China
  • MaxCard:
Home > Products >  99% Cisatracurium Besylate 96946-42-8 Muscle Relaxant

99% Cisatracurium Besylate 96946-42-8 Muscle Relaxant CAS NO.96946-42-8

  • Min.Order: 10 Gram
  • Payment Terms: T/T,
  • Product Details

Keywords

  • 99% Cisatracurium Besylate
  • Cisatracurium Besylate Manufacturer
  • Muscle Relaxant

Quick Details

  • ProName: 99% Cisatracurium Besylate 96946-42-8 ...
  • CasNo: 96946-42-8
  • Molecular Formula: C53H72N2O12.2C6H5O3S
  • Appearance: White Powder
  • Application: It Can Be Used As Pharmaceutical Inte...
  • DeliveryTime: 2-4 days after confirming your payment...
  • PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
  • Port: Wuhan
  • ProductionCapacity: 10000 Metric Ton/Month
  • Purity: 99%
  • Storage: Store in sealed containers at cool & d...
  • Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
  • LimitNum: 10 Gram

Superiority

 

Advantages:
 
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

 

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.


4. Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

Details

 

Cisatracurium besylate Basic information
Muscle relaxants Pharmacological effects Pharmacokinetics Clinical application Cisatracurium Besilate Dosage Suitable solvents Rate of administration Stability Side effects Taboo and caution Drug Interactions
Product Name: Cisatracurium besylate
Synonyms: (1r,1'r,2r,2'r)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium dibenzenesulfonate;cisatracurium besilate;cisatracurium besylate;1R-CIS,1R∧-CIS (CISATRACURIUM BESYLATE);Cisatracurium;Cisatrcurium Besylate;3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propionic acid 5-[3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl ester;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
CAS: 96946-42-8
MF: C53H72N2O12.2C6H5O3S
MW: 1243.49
EINECS: 1806241-263-5
Product Categories: Neuromuscular Blocking Agent;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs;Analgesic series
Mol File: 96946-42-8.mol
Cisatracurium besylate Structure
 
Cisatracurium besylate Chemical Properties
Melting point  90-93°C
storage temp.  Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility  H2O: soluble1mg/mL
color  white
 
Safety Information
Hazard Codes  T
Risk Statements  25-36
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
 
Cisatracurium besylate Usage And Synthesis
Muscle relaxants Cisatracurium besylate is the benzene sulfonate salt form of atracurium. It is a kind of artificially synthetic non-depolarizing muscle relaxants with its role similar as tubocurarine. It has an onset time of 1 minute and duration time of 15 minutes. The treatment dose does not affect the heart, liver and kidney function. It also has no accumulation property. It also can induce the release of histamine when used at large doses. For muscle relaxation or breathing control required in surgery, compared with current clinical major muscle-relaxing anesthetic drugs, cisatracurium besylate is not metabolized through liver or kidney, and has cardiovascular stability; its effect of muscle relaxation is 3 times as strong as atracurium without any cardiovascular side effects. Cisatracurium besylate is mainly applied to general anesthesia, and can be widely used in intubation, treating liver and kidney dysfunction, used in cardiovascular surgery and elderly and pediatric patients. 
Compared with atracurium, this product has no dose-dependent adverse effects of histamine release; however, the disadvantage is that patients with liver and kidney dysfunction should administrate with caution. 
Since 1996 for the first time when this drug has entered into market in UK, foreign countries have gradually applied it to replace vecuronium and atracurium as the mainstream of clinical muscle relaxants.
Pharmacological effects The mechanism of action of cisatracurium besylate is similar with that of tubocurarine chloride; but this product is a kind of non-depolarizing muscle relaxant drugs which is mainly used for blocking the transmission of nerve impulses, boost muscle relaxation and can release histamine; but it has a lower effect than tubocurarine alkaline; it is characterized by a rapid onset and a high muscle relaxant effect.
Pharmacokinetics After its intravenous injection of the product into the body tissue, it rapidly play a pharmacological effect in the target, and can further pass through the placenta into the fetal circulation.
Clinical application Clinically, it is generally used for maintaining muscle relaxing or facilitating the mechanical respiration; larger doses can be used for endotracheal intubation.
Chemical Properties White Solid
Uses Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
Uses An enantiomer of Atracurium Besylate (A794500). A neuromuscular blocking agent. It could be used in liver transplant patient with safety.
Definition ChEBI: The (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. isatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia.

 

Other products of this supplier

lookchemhot product CAS New CAS Cas Database Article Data Chemical Catalog