high quality 90779-69-4 Atosiban with best price CAS NO.90779-69-4

Min.Order: 10 Gram
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Atosiban
90779-69-4
90779-69-4 Atosiban

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ProName: high quality 90779-69-4 Atosiban w...
CasNo: 90779-69-4
Molecular Formula: C45H71N11O14S2
Appearance: White Crystalline Powder
Application: It Can Be Used As Pharmaceutical Inte...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: shanghai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

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high quality 90779-69-4 Atosiban with best price

Atosiban Basic information

Product Name:	Atosiban
Synonyms:	1-deamino-2d-tyr-(oet)-4-thr-8-orn-oxytocin;oxytocin,1-(3-mercaptopropanoicacid)-2-(o-ethyl-d-tyrosine)-4-l-threonine-8-l;Atosiban Impurtiy;rwj22164;ATOSIBAN ACETATE;1-(3-Mercaptopropionic acid)-2-(3-(p-ethoxyphenyl)-D-alanine)-4-L-thre onine-8-L-ornithineoxytocin;[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2;(2S)-N-[(1S)-4-Amino-1-(carbamoylmethylcarbamoyl)butyl]-1-[(4S,7S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
CAS:	90779-69-4
MF:	C45H71N11O14S2
MW:	994.19
EINECS:	806-815-5
Product Categories:	Peptide;hormones
Mol File:	90779-69-4.mol

Atosiban Chemical Properties

storage temp.	−20°C
solubility	H₂O: ≤100 mg/mL
form	solid
CAS DataBase Reference	90779-69-4(CAS DataBase Reference)

Safety Information

WGK Germany	3
RTECS	RS7590000

MSDS Information

Atosiban Usage And Synthesis

Description	Atosiban was introduced in the UK as an injectable inhibitor of preterm labor, a major cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of the vasopressin V_1a receptor and of the oxytocin receptor which is found in dramatically increased concentration in the uterine myometrium of pregnant women near term. It competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with atosiban caused pregnancy prolongation for up to 7 days in women with more than 28 weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic action (uterine relaxant) to ritodrine but the former was significantly better tolerated, especially with regards to maternal cardiovascular side effects. In healthy volunteers, plasma levels of atosiban decreased bi-exponentially with an initial and a terminal half-life of 21 min and 1.7h respectively.
Originator	Ferring AB (Sweden)
Uses	Premature labor
Uses	Atosiban is an oxytocin receptor blocking agent in the treatment of experimental endometriosis and was shown exhibit significant therapeutic efficiency.
Brand name	Tractocile, Antocin
Anticancer Research	The antitumor effects of the essential oil of O. falcata were tested in transplantedmurine H22 solid tumors in vivo. Growth inhibition in H22 solid tumors was moderate(Yang et al. 2013).

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