High Quality Temozolomide Powder in Stock/CAS: 85622-93-1 with best price CAS NO.85622-93-1

Min.Order: 100 Gram
Payment Terms: T/T,

Product Details

Keywords

85622-93-1
Temozolomide
C6H6N6O2

Quick Details

ProName: High Quality Temozolomide Powder in St...
CasNo: 85622-93-1
Molecular Formula: C6H6N6O2
Appearance: White Powder
Application: Used as a pharmaceutical intermediates...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

Superiority

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

Details

High Quality Temozolomide Powder in Stock/CAS: 85622-93-1 with best price

Details:

Temozolomide: 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
Molecular Structure:
Molecular Formula: C6H6N6O2
Molecular Weight: 194.15
CAS No.: 85622-93-1
Uses: Antitumor Drug
Purity: >99%
Temozolomide is a chemotherapy drug used to treat certain types of brain tumours called glioblastoma multiforme or anaplastic astrocytoma.

Description:

Temozolomide is an antitumor, antiangiogenic compound that has been shown to work by alkylating DNA, typically through addition of a methyl group to guanine in genomic DNA. The efficacy of this compound is dependent on its ability to methylate the DNA, thus triggering apoptosis;
however, some cells are able to repair this damage via the enzymes O-6-methylguanine-DNA methyltransferase (MGMT). As a consequence, temozolomide is far more efficacious in tumor cells that have silenced this repair enzyme. Research has also been conducted to determine whether MGMT inhibitors such as O-6-benzylguanine might help to increase the efficacy of temozolomide. Furthermore, temozolomide has been implicated in causing arrest at the G2/M cell cycle checkpoint, which mightalso play a role in its cytotoxicity.

COA:

Test items	Requirements	Results
Description	A White or off-white crystalline powder; odorless; tasted bitter.	Complies
Solubility	Slightly soluble in water, very slightly soluble in dehydrated alcohol, soluble in DMF and very soluble DMSO.	Complies
Identification
A. IR	A: Conform to reference standard	Conforms
B. Chemical Property	B: Dissolve 0.1g the sample with 10ml water, add 5ml dinitro-phenyl-hydrazine, should have marron precipitate.	Positive
C. HPLC	C: The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation	Conforms
Loss on drying	≤ 1.0%.	0.21%
Residue on ignition	≤ 0.1%.	0.07%
Heavy metals	≤ 0.002%.	Complies
Chloride	≤ 0.002%.	Complies
Impurities by HPLC Any impurity(Max) Total impurities	≤ 0.1%. ≤ 0.3%.	0.042% 0.08%
Residual solvents Ethyl acetate Alcohol DMSO	≤ 0.5%. ≤ 0.5%. ≤ 0.5%.	Complies Complies Complies
Assay (HPLC)	98.5%~102.0%	99.80%

Advantages:

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.

3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.

4. Warm after-sale service Any of your question would be solved for the first as soon as possible.