Raloxifene Cancer Treatment Steroids Yellow Powder CAS 84449-90-1Pharmaceutical

 

Quick detail

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Name:	Raloxifene
CAS No.:	84449-90-1
Formula:	C28H27NO4S
Molecular Weight:	473.58
Synonyms:	Keoxifene;LY 139481;[2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][4-(2-(1-piperidinyl)ethoxy)phenyl]methanone;
Density:	1.289 g/cm3
Melting Point:	250-253 °C
Boiling Point:	728.2 °C at 760 mmHg
Flash Point:	394.2 °C
Solubility:	DMSO: 28 mg/mL, soluble
Appearance:	light-yellow solid

 

Raloxifene ?Description

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• Raloxifene is used to prevent and treat osteoporosis (condition in which the bones become thin and weak and break easily) in women who have undergone menopause (change of life; end of menstrual periods). Raloxifene is also used to decrease the risk of developing invasive breast cancer (breast cancer that has spread outside of the milk ducts or lobules into the surrounding breast tissue) in women who are at high risk of developing this type of cancer or who have osteoporosis.
• Raloxifene cannot be used to treat invasive breast cancer or to prevent invasive breast cancer from coming back in women who have already had the condition.
• Raloxifene also cannot be used to decrease the risk of developing non-invasive breast cancer.
• Raloxifene is in a class of medications called selective estrogen receptor modulators (SERMs).
• Raloxifene prevents and treats osteoporosis by mimicking the effects of estrogen (a female hormone produced by the body) to increase the density (thickness) of bone.
• Raloxifene decreases the risk of developing invasive breast cancer by blocking the effects of estrogen on breast tissue. This may stop the development of tumors that need estrogen to grow.

 

Raloxifene is used for

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Raloxifene is approved to prevent:	Breast cancer. It is used to decrease the chance of invasive breast cancer inpostmenopausal women who have a high risk for developing the disease or who have osteoporosis.
Raloxifene hydrochloride is also approved to prevent and treat:	Osteoporosis in postmenopausal women. Raloxifene is also being studied in the treatment of other types ofcancer.

 

How Raloxifene Is Given

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• Raloxifene is given to you in a pill form. There is no intravenous (IV) preparation available. Take this medicine with a full glass of water, at the same time each day. If you miss a dose, do not take a double dose the next day. This medicine is to be taken once a day.
• In addition to Raloxifene, your healthcare provider may recommend that you take a calcium supplement with vitamin D (Vitamin D helps the calcium be absorbed better).
• The amount of Raloxifene that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and length of time you will take Raloxifene.

 

Monitoring and Testing

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1. Your health care provider will want to do blood tests to see how well you are responding to Raloxifene. Keep all appointments for tests, and office visits.
2. Women will need a gynecologic (GYN) examination before therapy, and during therapy, at regular intervals. Discuss the appropriate schedule with your healthcare provider.
3. Bone mineral density (BMD) should be done periodically to determine how strong your bones are. You may need this at least every 2 years, or sooner if your healthcare provider suggests.
4. Your doctor may also monitor other types of blood work, to see if the medication is affecting other parts of your body.