USP, 98.0% Purity Pharmaceutical Raw Materials Simvastatin (CAS 79902-63-9) CAS NO.79902-63-9

Min.Order: 100 Gram
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Product Details

Keywords

79902-63-9
Simvastatin
Bactericide

Quick Details

ProName: USP, 98.0% Purity Pharmaceutical Raw M...
CasNo: 79902-63-9
Molecular Formula: C25H38O5
Appearance: white or almost white powder
Application: Pharmaceutical Raw Materials
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

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Details

USP, 98.0% Purity Pharmaceutical Raw Materials Simvastatin (CAS 79902-63-9)

Product Description

Product Name: Simvastatin
Chemical Name:
1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste(7-beta,8-beta(2s*,4s*),8a-beta))-alph
CAS NO.: 79902-63-9
EINECS NO.: 404-520-2
Molecular Formula:C25H38O5
Formula Weight:418.57
Structural formula:
USP, 98.0% Purity Pharmaceutical Raw Materials Simvastatin (CAS 79902-63-9)
Properties:
Appearance and solubility: White crystalline powder,odorless. Practically insoluble in water, freely soluble in chloroform, in methanol and in alcohol; sparingly soluble in propylene glycol; very slightly soluble in hexane.
Density: 1.11 g/cm3
Melting point: 139 ºC
Boiling point: 564.9 139 ºC at 760 mmHg
Flash point: 184.8 139 ºC
Refractive index: 1.53

Quality Specification: USP35,≥98.0%

TESTS			SPECIFICATION	RESULTS
Characters			white or almost white powder	Conforms
Identification	A.IR		Conforms	Conforms
	B.the retention time of the major Peak		Conforms	Conforms
Specific rotation			+285° ~ +298°	+291.5°
Solubility			Practically insoluble in water; freely soluble in chloroform, in methanol and in alcohol; sparingly soluble in propylene glycol; very slightly soluble in hexane	Conforms
Loss on drying %			≤0.5%	0.25%
Residue on ignition %			≤0.1%	0.02%
Heavy Metals %			≤0.001	Conform
Related Substance		Simvastatin hydroxyacid	≤0.4%	0.06
		Epilovastatin and Lovastatin	≤1.0%	0.26
		Methylene simvastatin	≤0.4%	0.07
		Acetyl simvastatin	≤0.4%	0.06
		Anhydro simvastatin	≤0.4%	0.06
		Simvastatin dimer	≤0.4	0.08
		Any other individual impurity	≤0.1%	Complies
		Total impurities other than lovastatin and epilovastatin	≤0.1%	0.36
Assay %(on dried basis)			98.0-102.0	99.4
Conclusion: Complies with USP35

Application:
1. HMG-CoA reductase inhibitors, can reduce the concentration of serum total cholesterol level, inhibit synthesis of cholesterol. For treatment of primary hypercholesterolemia with cholesterol levels greater than 7.8mmol/L which is invalid or not tolerated in other treatments.
2. Has role in reducing cholesterol, low-density lipoprotein cholesterol and very low density lipoprotein cholesterol.

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