high quality641571-10-0 Nilotinib with best price CAS NO.641571-10-0

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Basic info:

Product name: Nilotinib Intermediate
CAS: 641569-94-0
Molecular Formula: C17H14N4O2
Molecular weight:306.32
Stability: Stable
Product description: Potent precision of the second generation of tyrosine kinase inhibitors, effective treatment for drug resistance or intolerance of patients with chronic myeloid leukemia.

Nilotinib in the form of the hydrochloride monohydrate salt, is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.Structurally related to imatinib, it was developed based on the structure of the Abl-imatinib complex to address imatinib intolerance and resistance. Nilotinib is a selective Bcr-Abl kinase inhibitor that is 10-30 fold more potent than imatinib in inhibiting Bcr-Abl tyrosine kinase activity and proliferation of Bcr-Abl expressing cells.

Specification:

Functions:

Antineoplastic Agents

Advantages:
 
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