OVERVIEW
CAS No.: 135463-81-9
English name: COLURACETAM
English synonym: BCI-540; COLURACETAM; Coluracetam, >=99%; Coluracetam, MKC-231; coluracetam cas: 135463-81-9; 2-oxo-N-( 5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl)-1-pyrrolidineacetamide; 1-Pyrrolidineacetamide, 2-oxo-N-(5,6, 7,8-tetrahydro-2,3-dimethylfuro[2,3-b]quinolin-4-yl)-;N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b ]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide; 1-[N-(2,3-DiMethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin -4-yl)carbaMoylMethyl]pyrrolidin-2-oneChemicalBook
Overview of the properties, uses and production processes of kolaracetam
The chemical name of coluracetam is N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b] Quinoline-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide is a class of sittans under development and belongs to the class of derivatives. With its unique mechanism of action, remarkable efficacy, and extremely low toxicity, it can be widely used in the clinical treatment of diseases such as cognitive dysfunction and epilepsy. This variety of kolaracetam is currently in clinical trials.
Physical and chemical properties
Density: 1.291g/cm3
Boiling point: 634.1oC at 760 mmHg
Flash point: 337.3oC
Refractive index: 1.64
Vapor pressure: 5.54E-16mmHg at 25°C
Pharmacological action
Koracetam by increasing the neurites by participating in the HACU process The rate-limiting step of ingesting choline to synthesize the neurotransmitter acetylcholine increases the activity of cholinergic neurons and has the ability to improve cognition. Clinical trials to adapt to symptoms
1. For the use of drugs. It can be used to treat memory and mental disorders caused by Alzheimer's disease, mild to moderate vascular dementia, traumatic disorders, and to promote mental development in children.
2. Antidepressant effect. By promoting the transmission of nerve signals, it has a significant effect on depression. The above information about the physical and chemical properties of the kalacetam, pharmacological effects.
China (Mainland)
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