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Oxytocin Manufacturer 50-56-6 With Factory Best Price CAS NO.50-56-6
- Min.Order: 10 Gram
- Payment Terms: T/T,MoneyGram
- Product Details
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- 99% Oxytocin
- Oxytocin Manufacturer
- Pharmaceutical Raw Materials
Quick Details
- ProName: Oxytocin Manufacturer 50-56-6 With Fac...
- CasNo: 50-56-6
- Molecular Formula: C43H66N12O12S2
- Appearance: White Powder
- Application: It Can Be Used As Pharmaceutical Inte...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 10 Gram
Superiority
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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Details
| Oxytocin Basic information |
| Product Name: | Oxytocin |
| Synonyms: | (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-[(2S)-butan-2-yl]-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)-3-methyl-butyl]pyrrolidine-2-carboxamide;OXYTOCINACETATE,VETERINARY;H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, (Disulfide bond);Oxytocin (Veterinary Grade);Human Oxytocin;Hyphotocin;Intertocine S;L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide Cyclic (1-6)-Disulfide |
| CAS: | 50-56-6 |
| MF: | C43H66N12O12S2 |
| MW: | 1007.19 |
| EINECS: | 200-048-4 |
| Product Categories: | Amino Acid Derivatives;Organics;Amino Acids 13C, 2H, 15N;Peptide;Amino Acids & Derivatives;Intermediates & Fine Chemicals;hormones;peptides for birth-giving use;Veterinary drugs;Pharmaceuticals;Vasopressin and Oxytocin receptor;Peptide Receptors |
| Mol File: | 50-56-6.mol |
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| Oxytocin Chemical Properties |
| Melting point | 192-194°C |
| alpha | D22 -26.2° (c = 0.53) |
| density | 1.1086 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | 2-8°C |
| solubility | Very soluble in water. It dissolves in dilute solutions of acetic acid and of ethanol (96 per cent). |
| form | lyophilized powder |
| pka | pKa ～6.1(free amino group on Cys) (Occasionally);～10(free phenol on Tyr) (Occasionally) |
| color | White |
| Water Solubility | Soluble in water. |
| Merck | 13,7049 |
| BRN | 3586108 |
| InChIKey | DSZOEVVLZMNAEH-BXUJZNQYSA-N |
| CAS DataBase Reference | 50-56-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | RS7534000 |
| F | 3-8-10-23 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Hazardous Substances Data | 50-56-6(Hazardous Substances Data) |
| Oxytocin Usage And Synthesis |
| Indications and Usage |
Oxytocin (OT) is a type of uterine contraction drug and can be derived from the animal posterior pituitary or chemically synthesized. Oxytocin is a uterine contraction drug that is mostly used in late pregnancy induction and stagnant birth due to weak uterine contractions. Suitable for inducing labor and alleviating pain. Commonly used with ergot preparations to be used in inducing labor, expediting labor, and in uterine bleeding due to weak uterine contractions following birth or still birth. Nose drops can be used to promote lactation. |
| Mechanisms of Action | Oxytocin does not contain vasopressin and has no pressure-boosting effects. It can be absorbed through oral mucosa, selectively excite smooth uterine muscle, and intensify its contractions. The uterus is most sensitive to oxytocin when in labor (due to increased estrogen secretion), and an immature uterus will not respond to this drug. During early or mid-term pregnancy, the uterus has a relatively low reactivity to oxytocin, which gradually increases during late-stage pregnancy and peaks during labor. Small doses can strengthen the rhythmic contractions of smooth uterine muscles, increase their contractibility, increase their contraction speed, ensure similar contraction characteristics to that of a natural birth, and maintain polarity and symmetry. Thus, it is used clinically to expedite and induce labor. Large doses cause tonic contractions in the uterine muscles, so it is used clinically to burst blood vessels between muscle fibers, prevent postpartum hemorrhage, and ensuring postpartum recovery. It can also promote lactation by causing the breast ducts to contract and expel milk from the breasts, but it cannot increase the lactation amount. |
| Pharmacokinetics | Ineffective when taken orally, as it can be damaged by digestive fluids, although it can be absorbed through oral mucosa. 1-3 minutes of venous infusion 0.01 IU can induce physiological uterine contractions (Rhythmic, polar, symmetrical) with a short time span, as its half-life is only 2.5-3 minutes. Large doses cause tonic uterine contractions. |
| Adverse reactions | Oxytocin derived from cow or pig’s pituitary occasionally causes allergic reactions, and infusing too quickly may lead to mild vasodilation and hypotension. Patients who suffer from abruptio placentae, heart disease, or enlarged uterus, are over 35 years old, have a history of cesarean section or uterine muscle tumor removal, or are experiencing a breech birth should use with caution. Using oxytocin while experiencing a sacral block may lead to severe hypertension and even cerebrovascular rupturing. Cannot be injected in the same solution with norepinephrine. Incompatible with hydrolyzed proteins. |
| Contradictions | Do not use during birth if there are obvious signs of an unsymmetrical head, incorrect fetal position, exposed umbilical cord, prolapse, complete placenta previa, narrow pelvis, or overly intense uterine contractions. Not to be used by patients with overly narrow pelvises, histories of uterine surgery (including C-sections), excessive pains, blocked birth canals, abruptio placentae, or pregnancy poisoning. |
| Warnings and Precautions | Dosage and infusion speed must be strictly monitored when used to expedite or induce labor to prevent tonic contractions, which can suffocate the fetus or rupture the uterus. |
| Chemical Properties | White Solid |
| Uses | Oxytocin is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland. |
| Definition | ChEBI: A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is bel eved to influence social cognition and behaviour. |
| Uses | Oxytocin is a nonapeptide hormone primarily synthesized in magnocellular neurons of the paraventricular and supraoptic nuclei of the hypothalamus. It is known best for its role in stimulating uterine contraction and lactation and is important for social memory and attachment, sexual and maternal behavior, and aggression. Also, it has been implicated in various non-social behaviors, including learning, anxiety, feeding, and pain perception. |