Pazopanib CAS:444731-52-6 Pharmaceutical Raw Materials

Pazopanib (CAS:444731-52-6)

Product Name: Pazopanib
Other Name:Pazopanib for research;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;Pazopanib;Pazopanib(GW786034);5-(4-((2,3-diMethyl-3,3a-dihydro-2H-indazol-6-yl)(Methyl)aMino)pyriMidin-2-ylaMino)-2-MethylbenzenesulfonaMide;5-[(4-{[(2,3-diMethyl-2H-indazol-6-yl)Methyl]aMino}pyriMidin-2-yl)aMino]-2-Methylbenzene-1-sulfonaMide;5-({4-[(2,3-diMethyl-2H-indazol-6-yl)(Methyl)aMino]pyriMidin-2-yl}aMino)-2-MethylbenzenesulfonaMide 5-(4-(N-(2,3-diMethyl-2H-indazole-6-yl)- N-MethylaMino)pyriMidine-2-ylaMino)-2-MethylbenzenesulfonaMide;Votrient
CAS No.: 444731-52-6
Molecular Formula: C21H23N7O2S
Molecular Weight:437.52
Purity: 99%+
Product Specifications: Pharmaceutical Grade
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT
 

Pazopanib is a chemotherapeutic agent a doctor may prescribe as part of the treatment plan for renal cell carcinoma and certain other cancers.
1.Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit.
2.Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.
3.An oral angiogenesis inhibitor targeting VEGFR and PDGFR.
4.The medication is used to treat clear cell variant renal cell carcinoma.
5.The treatment phase is continuing treatment beyond 3-months.
6.The patient has been issued an authority prescription for pazopanib
7.The patient must have stable or responding disease according to the 8.Response Evaluation Criteria In Solid Tumours (RECIST)
9.This treatment must be the sole tyrosine kinase inhibitor subsidised for this condition.

 
 
 
 
Advantages:
 
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Pazopanib CAS:444731-52-6 Pharmaceutical Raw Materials