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Home > Products >  USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment

USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment CAS NO.439081-18-2

  • Min.Order: 100 Gram
  • Payment Terms: T/T,Western Union,MoneyGram
  • Product Details

Keywords

  • 439081-18-2
  • Afatinib
  • BIBW 2992

Quick Details

  • ProName: USP Kinase Inhibitors Afatinib 439081-...
  • CasNo: 439081-18-2
  • Molecular Formula: C24H25ClFN5O3
  • Appearance: White crystal powder
  • Application: Lung Cancer Treatment
  • DeliveryTime: 2-4 days after confirming your payment...
  • PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
  • Port: Wuhan
  • ProductionCapacity: 20000 Kilogram/Day
  • Purity: 99%
  • Storage: Store in sealed containers at cool & d...
  • Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
  • LimitNum: 100 Gram

Superiority

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

 

Details


Product Description

 

USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment 

1. Quick Details:
 

Product name:

Afatinib (BIBW 2992);Gilotrif

Synonyms:

BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Tovok;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylaMino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(diMethylaMino)but-2-enaMide

CAS:

439081-18-2

MF:

C24H25ClFN5O3

MW:

485.944

Purity:

99.5% min 

Appearance:

White or Nearly White Crystalline Powder

MOQ:

10G

Specifications:

Pharmaceutical Grade

Deliver time:

About 5 days

Deliver methods:

TNT,EMS,HKEMS,DHL,ect.(door to door)

 


2. What is Afatinib

Afatinib is pronounced aff-a-tin-ib. It has the brand name Giotrif (jee-oh-triff). It is a type of biological therapy called a tyrosine kinase inhibitor (TKI). It is a treatment for non small cell lung cancer that has spread outside the lung or to other parts of the body.

It has received regulatory approval for use as a treatment for non-small cell lung cancer,although there is emerging evidence to support its use in other cancers such as breast cancer.

3. How afatinib works:

This type of drug works by blocking particular proteins on cancer cells that encourage the cancer to grow. Afatinib blocks proteins called epidermal growth factor receptors (EGFR). Cancers that have these receptors are called EGFR positive.

Between 10 and 15 people out of every 100 with non small cell lung cancer (10 to 15%) have EGFR positive cancer. Doctors check your cancer cells to see if they have the receptors before you have this treatment.

Afatinib may shrink the cancer or stop it growing for a time

4. Uses and fuction:

Afatinib is used to treat a certain type of lung cancer (non-small cell lung cancer) that has spread to other parts of the body. It belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells. It binds to a certain protein (epidermal growth factor receptor-EGFR) in some tumors.

5. Mechanism of action:

Like lapatinib and neratinib, afatinib is a protein kinase inhibitor that also irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases. Afatinib is not only active against EGFR mutations targeted by first generation tyrosine-kinase inhibitors (TKIs) likeerlotinib or gefitinib, but also against mutations such as T790M which are not sensitive to these standard therapies.Because of its additional activity against Her2, it is being investigated for breast cancer as well as other EGFR and Her2 driven cancers.

6. COA:
 

Item

Requirements

Test Results

Description

Off-white powder

Off-white powder

Identification

HPLC ,NMR

Complies

Residue on Ignition

≤0.10%

0.05%

Loss on Drying

≤0.50%

0.15%

Heavy Metal

≤20ppm

<20ppm

Purity(HPLC)

≥99.0%

99.99%

Conclusion

It complies with EnterpriseStandard

 

Advantages:

 

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

 
USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment 

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