Citicoline sodium CAS 33818-15-4 CAS NO.33818-15-4

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Citicoline sodium

CAS: 33818-15-4

MF: C14H26N4O11P2.Na

MW: 511.31

EINECS: 251-689-1

Melting point 259-268°C (dec.)

alpha D20 +12.5° (c = 1.0 in H2O)

storage temp. -20°C

solubility H2O: 100mg/mL

form solid

color white

Water Solubility Soluble in water (100 mg/ml).

Chemical Properties White Solid

Uses Naturally occurring nucleotide; intermediate in the major pathway of lecitin biosynthesis. Neuroprotective. It is used in the treatment of ischemic stroke and head trauma.

Uses Cytidine 5′-diphosphate (CDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) to produce CTP in support ofDNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

Uses Cytidine-5'-diphosphocholine sodium salt hydrate acts as a neuroprotective agent in situations of hypoxia and ischemia. It is used as biosynthetic intermediate of membrane phospholipids. It is a cerebral vasodilator and inhibits PLA2 activation.

Application Citicoline (CDP-choline) is an essential intermediate in the synthesis of the major phospholipid of the cell membranes, phosphatidylcholine (PtdCho). It increases plasma adrenocorticotropic hormone (ACTH) levels and potentiates serum thyrotrophin (TSH) levels by activating the central cholinergic system.

Citicoline Sodium is used to treat age-related memory loss, cerebrovascular diseases such as stroke, dementia, as well as head trauma. Research has shown that it increases a chemical called phosphatidylcholine which is important for brain function. Citicoline might also decrease brain tissue damage when the brain is injured. Citicoline Sodium is also said to help with weight management when used as a dietary supplement.