Hot Selling Factory Supply 10-Deacetylbaccatin III CAS 32981-86-5 CAS NO.32981-86-5

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10- Deacetylbacartine III is a white crystalline powder soluble in methanol, ethanol, DMSO and other organic solvents. It is used as an intermediate in the synthesis of taxol and its derivatives.

Function

10-Deacetyl Baccatin III or 10-DAB III is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented.By extracting the pre-cursor 10-DAB III in large quantites from the Taxusbaccata leaf, many subsequent semiayntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and therefore the pharmacological
profile of these important chemo-therapeutic agents.

♦ Taxan-derivatives have gained great attention because of their partly excellent anti-cancer properties.
♦10-Deacetyl-baccatin-III (10-DAB) can be gained from the leaves of yew trees and it is used as starting materials for numerous partial syntheses