High purity CAS NO.314728-85-3 Piperazine CAS NO.314728-85-3

introducation:

sunifiram is a research ampakine that is becoming very popular amongst researchers. sunifiram (dm-235) is a piperazine derived ampakine drug which acts as a positive allosteric

modulator of ampa receptors, and has nootropic effects in animal studies with significantly

higher potency thanpiracetam. a number of related compounds are known, the best known

being unifiram (dm-232)

this enhancement by sunifiram is associated with an increase inphosphorylation of ampar through activation of protein kinase ii(camkii) and an increase in phosphorylation of nmdar through activation of protein kinase c α (pkcα). more specifically, sunifiram stimulates the glycinebinding site of nmdar with concomitant pkcαactivation through src kinase. enhancement of pkcα activity triggers to potentiate hippocampal ltp through camkii activation. sunifiram improves cognitive deficits via cam kinase ii andprotein kinase c activation.

function:

enhance mental intelligence; boost memory and leaning capabilities; improve brain power to solve problems and protect it from any chemical or physical injury; enhance motivation level;enhance the control of cortical/subcortical brain mechanism; improve sensory perception.

specification:

superiority of choosing our company

•Pharmaceutical raw materials

•Chemical raw materials

•Food additives

•Flavors and fragrances

•Feed additives

•Plant extracts

•Veterinary raw materials

We could supply you:

•Best quality

•Competitive price

•Perfect services

We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

sunifiram is a research ampakine that is becoming very popular amongst researchers. sunifiram (dm-235) is a piperazine derived ampakine drug which acts as a positive allosteric

modulator of ampa receptors, and has nootropic effects in animal studies with significantly

higher potency thanpiracetam. a number of related compounds are known, the best known

being unifiram (dm-232)

this enhancement by sunifiram is associated with an increase inphosphorylation of ampar through activation of protein kinase ii(camkii) and an increase in phosphorylation of nmdar through activation of protein kinase c α (pkcα). more specifically, sunifiram stimulates the glycinebinding site of nmdar with concomitant pkcαactivation through src kinase. enhancement of pkcα activity triggers to potentiate hippocampal ltp through camkii activation. sunifiram improves cognitive deficits via cam kinase ii andprotein kinase c activation.

enhance mental intelligence; boost memory and leaning capabilities; improve brain power to solve problems and protect it from any chemical or physical injury; enhance motivation level;enhance the control of cortical/subcortical brain mechanism; improve sensory perception.

Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.

We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.

We have won ISO 9001:2000 certification. and our quality control Dept. is engaged in the activities for securing stable product quality. and it is responsible for the guidance with and the management of quality assurance activities of the entire company in order to ascertain that our manufacturing activity could be carried out in compliance with the related laws, regulations and ISO standard.