Veterinary Medicine Anthelmintic Flubendazole CAS Number:31430-15-6 Supplier CAS NO.31430-15-6

Anthelmintic Flubendazole

CAS Number:31430-15-6

MF:C16H12FN3O3

EINECS:250-624-4

Density:1.444 g/cm3

Melting Point:290 °C

Package: 25kg/drum

Standard:Enterprise Standard

Purity : 99%

Usage:

Flubendazole is a synthetic benzimidazole de-worming drugs, can inhibit the absorption of cells of the worm microtubule polymerization.

Flubendazole is a broad-spectrum anthelmintic, effective in treatment of dogs in vivo parasites, such as gastrointestinal roundworm, hookworm, whipworm; but also pigs and poultry, the body can be treated in many gastrointestinal parasites, such as large Pig roundworm (Ascaris suum), stomach red pig round worm (Hyostrongylus rubidus), there are Oesophagostomum (Oesophagostomum dentatum), pig whipworm (Trichuris suis), lung, after a round worm (Metastrongylus apri) and so on. Flubendazole can not only kill the adult, it can also kill eggs.

 

 

Flubendazole is a synthetic anthelmintic belonging to the benzimidazole carbamates which acts by inhibiting the microtubular assembly in absorptive cells of nematodes. It acts by binding to tubulin, the dimeric subunit protein of the microtubules. It inhibits microtubular assembly in absorptive cells: i.e. of intestinal cells of nematodes. This is shown by disappearance of cytoplasmic microtubules, accumulation of secretory granules in the cytoplasm due to a block in their transport, leading to an impaired coating of the cellular membrane and a decreased digestion and absorption of nutrients. Irreversible lytic degeneration of the cell, due to the accumulation of secretory substances (hydrolytic and proteolytic enzymes), results in the death of the parasite.