- Product Details
Keywords
- 284461-73-0
- Sorafenib Tosylate
- Sorafenib
Quick Details
- ProName: 99.0% Purity Pharmaceutical Raw Materi...
- CasNo: 284461-73-0
- Molecular Formula: C21H16ClF3N4O3
- Appearance: Light Yellow Solid
- Application: Anti-Tumor Drugs
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 20000 Kilogram/Day
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 100 Gram
Superiority
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
5. High quality & competitive price;
Details
99.0% Purity Pharmaceutical Raw Materials Sorafenib CAS 284461-73-0
Product Name: Sorafenib
Chemical Name:4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide
CAS NO.: 284461-73-0
Molecular Formula:C21H16ClF3N4O3
Formula Weight:464.83
Structural formula:
Properties:
Appearance: Off white to white crystalline powder.
Density: 1.454 g/cm3
Melting point: 202-204 ºC
The boiling point of 523.3 ºC at 760 mmHg
Flash point: 270.3 ºC
Steam pressure: 4.76E-11mmHg at 25 ºC
Quality Specification:
Enterprise Standard,≥99.0%
ITEM | Specification | Results |
Characters | Off white to white crystalline powder | Off white crystalline powder |
Each related substances | NMT 0.5% | Complies |
Loss on drying | NMT 0.5% | 0.16% |
Sulphated ash | NMT 0.5% | 0.13% |
Assay | NLT 99.0% | 99.65% |
Conclusion | The above product is conformed to the Enterprise Standard |
Sorafenib Descrption
Sorafenib is a new multi-targeted oral drug for the treatment of tumors. Its primary development goal is to treat gastrointestinal stromal tumors and metastatic kidney cells that are not responsive or unbearable to standard therapies.
Sorafenib can selectively target certain proteins of the receptor, which is considered plays a role in molecular switching in the tumor growth process. Its indications have been in the approval by the FDA United States.
Sorafenib Application:
1. Sorafenib tosylate (284461-73-0) is commonly used as a potent RAF kinase inhibitor.
2. Sorafenib tosylate (284461-73-0) is also used as antineoplastic drug.
3. Sorafenib is used to treat liver tumor cells that can not be surgically or distantly metastasized
4. Sorafenib is used to treat neovascular tumors that can not be operated
5. Sorafenib is used to treat radioactive iodine therapy is no longer effective local recurrence or metastasis, progressive differentiation of thyroid patients
Sorafenib VS placebo
The progression-free survival of the Sorafenib group was longer than that of the placebo group (5.8 vs 2.8 months at a risk ratio of 0.51), and Sorafenib significantly improved patient quality of life compared with placebo.
Sorafenib treatment is well tolerated, with major adverse reactions being controlled diarrhea, rash, fatigue, hand, foot syndrome, hypertension, hair loss, nausea / vomiting and loss of appetite
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
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