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Local Anesthesia Drugs 99% Articaine Hydrochloride Manufacturer CAS 23964-57-0 

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Product Description:

Articaine Hydrochloride,Articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. It is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia.

Articaine Hydrochloride,In comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like lidocaine, prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.

COA:
 
 

Articaine Hydrochloride COA:
 

 
 
Applications:

Usage:
Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures

In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia

In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine works well.


Applications:
Articaine is a local anaesthetic that has been approved overseas for several years.Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve.This action is prolonged by combining the drug with a vasoconstrictor .

The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.