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Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4 CAS NO.21187-98-4
- Min.Order: 100 Gram
- Payment Terms: T/T,MoneyGram
- Product Details
Keywords
- 21187-98-4
- Gliclazide
- CAS 21187-98-4
Quick Details
- ProName: Factory Supply High Purity 99% Pharmac...
- CasNo: 21187-98-4
- Molecular Formula: C15H21N3O3S
- Appearance: Powder
- Application: Used as a pharmaceutical intermediates...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 20000 Kilogram/Day
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 100 Gram
Superiority
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
5. High quality & competitive price;
Details
Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4
Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of insulin secretagogues, which stimulates β cells of the pancreas to release insulin. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of insulin containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage by hydrogen peroxide.
| Gliclazide Basic information |
| Product Name: | Gliclazide |
| Synonyms: | )-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta(c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n’-(3-azabicyclo(3.3.0)oct-3-yl)urea;s852;se1702 |
| CAS: | 21187-98-4 |
| MF: | C15H21N3O3S |
| MW: | 323.41 |
| EINECS: | 244-260-5 |
| Product Categories: | Pharmaceutical;Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Potassium channel;Aromatics;Sulfur & Selenium Compounds;Other APIs;Pharmaceutical intermediates;Anti diabetic |
| Mol File: | 21187-98-4.mol |
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| Gliclazide Chemical Properties |
| Melting point | 163-169 °C(lit.) |
| density | 1.2205 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | methylene chloride: soluble |
| form | powder |
| color | white |
| Merck | 14,4439 |
| InChIKey | BOVGTQGAOIONJV-UHFFFAOYSA-N |
| CAS DataBase Reference | 21187-98-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 21-36/38-46-62-63 |
| Safety Statements | 25-26-36/37-53-24/25 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | YT4500000 |
| Toxicity | LD50 orally in mice: >3 g/kg (Duhault) |
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to
insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate
4. Warm after-sale service Any of your question would be solved for the first as soon as possible.