Posaconazole powder, Posaconazole price CAS 171228-49-2 Posaconazole CAS NO.171228-49-2

Min.Order: 100 Gram
Payment Terms: T/T,

Product Details

Keywords

171228-49-2
Posaconazole
C37H42F2N8O4

Quick Details

ProName: Posaconazole powder, Posaconazole pric...
CasNo: 171228-49-2
Molecular Formula: C37H42F2N8O4
Appearance: White crystalline granules or powder.
Application: Used as a pharmaceutical intermediates...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

Superiority

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

Details

Posaconazole powder, Posaconazole price CAS 171228-49-2 Posaconazole

Introduction

Name:Posaconazole

CAS: 171228-49-2

MF:C37H42F2N8O4

Purity:more than 99%

Posaconazole (SCH-56592)

Appearance:White or off-white crystalline powder

Assay(Titration):98.0 to 102.0%

Specification

Test items		Standard	Result
Description		White to off- White powder	Conforms
Identification	IR	IR spectrum of sample is the same as working standard	Conforms
	HPLC	HPLC RT of the sample is the same as the working standard	Conforms
Melting point		165.0°C~169.0°C	165.8°C~167.0°C
Optical rotation		-23°~-29°	-27.4°
Loss on drying		NMT 1.0 %	0.17%
Residue on ignition		NMT 0.1 %	0.03%
Heavy metals		NMT 20ppm	Conforms
Related substances
Impurity A		NMT 0.1 %	Not detected
Impurity B		NMT 0.1 %	Not detected
Impurity C		NMT 0.1 %	0.02%
Single impurity		NMT 0.2 %	0.17%
Total impurity		NMT 1.0 %	0.60%
Assay		NLT 99.0%	99.0%

Function

Posaconazole is a broadspectrum triazole active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14ademethylase enzyme (IC50s range from 7-200 nM), which results in a disruption the synthesis of ergosterol, a key sterol necessary for fungal cell membrane integrity and for the function of certain membranebound proteins.Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14alpha demethylase, a cytochrome P450-dependent enzyme. Posaconazole is a sterol C14a demethylase inhibitor with an IC50 of 0.25 nM. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters membrane permeability and eventually leads to fungal cell lysis. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14alpha demethylase. Posaconazole is the most advanced candidate for the treatment of Chagas disease. Posaconazole has entered in a phase II clinical trial in the treatment of mycoses.

Packaging & Shipping

Supply Veterinary Drug 99% Milbemycin Oxime Powder CAS129496-10-2

Advantages:

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.

3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.