High quality CAS NO.1689-64-1 9-Hydroxyfluorene CAS NO.1689-64-1

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We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

Name : 9-Hydroxyfluorene

Synonyms : 9H-Fluoren-9-ol

CAS :1689-64-1

Molecular Formula: C13H10O

Molecular Weight:182.22

EINECS: 216-879-0

MP: 153-154 °C(lit.

Other name:TIMTEC-BBSBB007717;9h-fluoren-9-ol;DIPHENYLENECARBINOL;9-HYDROXY- FLUOREN:

9-HYDROXYFLUORENE; 9-FLUORENOL; Hydroxyfluoren;fluoren-9-ol

Fluorenol is an alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. Hydroxyfluorene can be converted to fluorenone by oxidation. It is a white-cream colored solid at room temperature.

Fluorenol is an alcohol derivative of fluorene and is being clasisfied as a eugeroic compound, promoting wakefulness. The company Cephalon investigated Fluorenol in comparison to the popular eugeroic drug modafinil. In their comparison research with rodents, they noted that Fluorenol was significantly more effective than modafinil (up to 39%). Although it has dopamine reuptake properties, they tend to be pretty weak.

Dopamine reuptake inhibitor: An increase in dopamine production is known to improve cognition. Hydrafinil plays a role as a dopamine reuptake inhibitor, increasing dopamine concentrations.

5-HT6 antagonist: Antagonism of 5-HT6 receptor can result to increase in norepinephrine and dopamine concentrations in the prefrontal cortex, as well as increasing the production of choline and glutamate in different parts of the brain. Makers of Hydrafinil theorize that it functions as a 5-HT6 receptor antagonist.

Increase Glutamate levels: As mentioned earlier, antagonism of 5-HT6 receptors increases the production of glutamate in the brain. This could lead to enhanced memory and learning process. There is a great possibility that Hydrafinil's function as a 5-HT6 receptor antagonist could result in the improvement of cognitive performance.

Increase Norepinephrine levels: Manufacturers of Hydrafinil claim that it increases norepinephrine levels specifically in the prefrontal cortex by antagonizing 5-HT6 receptor. Increase in concentrations of norepinephrine could result to improvement of cognition. However, there's no enough evidence to prove this theory.

Increase Histamine levels: Hydrafinil is known to enhance histamine levels in the hypothalamus. Histamine plays an important role in normalizing our circadian rhythm and regulating sleep-wake cycles.

Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.

We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.

We have won ISO 9001:2000 certification. and our quality control Dept. is engaged in the activities for securing stable product quality. and it is responsible for the guidance with and the management of quality assurance activities of the entire company in order to ascertain that our manufacturing activity could be carried out in compliance with the related laws, regulations and ISO standard.