Antineoplastic API Capecitabine,CAS no 154361-50-9 CAS NO.154361-50-9

Min.Order: 100 Gram
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Product Details

Keywords

154361-50-9
Capecitabine
C15H22O6N3F

Quick Details

ProName: Antineoplastic API Capecitabine,CAS no...
CasNo: 154361-50-9
Molecular Formula: C15H22O6N3F
Appearance: White to white crystalline powder
Application: Used as a pharmaceutical intermediates...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

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Details

Antineoplastic API Capecitabine,CAS no 154361-50-9

Specifications

Name: Capecitabine
CAS: 154361-50-9
Quality Standard: USP32/BP2007/EP7
Apperance: White crystalline power

Product Description:

Name: Capecitabine

CAS: 154361-50-9

Quality Standard: USP32/BP2007/EP7

Apperance: White crystalline power

Product Specification:

Name: Capecitabine
CAS No.:	154361-50-9
Content:	99.0% min
Appearance:	A white,Crystalline Powder or colorless crystals
Formula:	C15H22O6N3F
Molecular Weight	359.35
Moisture:	≤0.1%
Loss on Drying:	≤0.2%
Residue on ignition:	≤0.1%
Heavy Metals:	≤10PPM
Acidity or Alkalinity:	Conform
Chloride:	Conform
Readily Carbonizable Substances:	Conform
Ordinary Impurities:	Conform

Functions

Function and Usage:

Classification: Antineoplastic, antimetabolite
Action/Kinetics: An oral prodrug of 5'-deoxy-5-fluorouridine (5'DFUR) that is converted to 5-fluorouracil (5-FU). 5-FU is metabolized to 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) which cause cell injury in two ways. First, FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase to form a covalently bound ternary complex which inhibits the formation of thymidylate from uracil. Thymidylate is essential for the synthesis of DNA so a deficiency inhibits cell division. Secondly, nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate during RNA synthesis; this interferes with RNA processing and protein synthesis. Readily absorbed from the GI tract. Peak blood levels, capecitabine: 1.5 hr; peak blood levels, 5-FU: 2 hr. Food reduces the rate and extent of absorption. t1/2, capecitabine and 5-FU: 45 min. Metabolites excreted in the urine.

Packaging & Shipping

Supply Veterinary Drug 99% Milbemycin Oxime Powder CAS129496-10-2

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