Advance technology support CAS NO.144060-53-7 Febuxostat CAS NO.144060-53-7

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We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

Product name: Febuxostat

CAS No: 144060-53-7

MF: C16H16N2O3S

Molecular Weight: 316.3748

Purity:99%

Appearance:  Off- white to white crystalline powder  

Febuxostat (INN; trade names Adenuric [EU], Febutaz [India] and Uloric [US]) is a urate lowering drug, an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuricemia and chronic gout.

Febuxostat received marketing approval by the European Medicines Agency on April 21, 2008 and was approved by the U.S. Food and Drug Administration on February 16, 2009.

A study comparing febuxostat to allopurinol found that more individuals treated with febuxostat had decreased levels of uric acid, but there was no difference in the amount of initial gout flares or the surface area of gout tophi.

(1) the allopurinol only have inhibition to reduced the XOR, rather than cloth sutent XOR of oxidation and reduced significantly inhibitory effect, more powerful, durable and its effect in lowering uric acid;

(2) because allopurinol is a purine analogues, it is inevitable to affect the metabolism of other enzymes involved in purine and pyridine metabolism.So in allopurinol treatment, you need to repeat a large dose to maintain a high level of medication.It also leads to serious and even fatal adverse reactions caused by drug accumulation.Instead of being a non-purine XOR inhibitor, it has better security.

Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.

We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.

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