Pharmaceutical Intermediate Montelukast leukotriene D4 CAS 142569-70-8 CAS NO.142569-70-8

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Pharmaceutical Intermediate Montelukast leukotriene D4 CAS142569-70-8

 

Product info :

 

Name: 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol
Molecular Formula: C29H28ClNO2
Formula Weight: 457.99
CAS No.: 142569-70-8

Application : Usage An intermediate of Montelukast

 

About Montelukast :

Montelukast selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1.
Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. This reduces the bronchoconstriction otherwise caused by the leukotriene, and results in less inflammation.

 

Chemical Properties

 

Molecular Structure
Molecular Weight	457.99
Density	1.244g/cm3
Boiling Point	636.8°Cat760mmHg
Flash Point	338.9
Refractive index	1.686

Safety Information

 

Hazard Codes	Xi,N,C
Risk Statements	21/22-34-43-51/53
Safety Statements	22-26-36/37/39-45-61
Hazard Note	Irritant/Stench

 

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Pharmaceutical Intermediate Montelukast leukotriene D4 CAS142569-70-8