Atorvastatin Calcium

CAS: 134523-03-8
MF: C66H68CaF2N4O10
MW: 1155.36
Purity: 99%min.
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Storage: Stored in cool and dry place, keep away from strong light/heat.
Shelf Life: 2 years when properly stored.
Color:White crystalline powder



Product Description:

Lipitor (atorvastatin calcium) is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.

Atorvastatin calcium is a white to offwhite crystalline powder that is insoluble in aqueous solutions of pH 4and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.

Lipitor tablets for oral administration contain 10, 20, 40 or 80 mg atorvastatin and the following inactive ingredients: calcium carbonate, USP; candelilla wax, FCC; croscarmellose sodium, NF; hydroxypropyl cellulose, NF; lactose monohydrate, NF; magnesium stearate, NF; microcrystalline cellulose, NF; Opadry White YS17040 (hypromellose, polyethylene glycol, talc, titanium dioxide); polysorbate 80, NF; simethicone emulsion.

 

Application:

Atorvastatin Calcium , used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammation and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.


 

Function:

Used for primary hypercholesterolemia, combined hyperlipidemia or diet control invalid for patients with familial hypercholesterolemia.