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Hot Selling High Quality Nsi-189 1270138-41-4 with Reasonable Price and Fast Delivery CAS NO.1270138-41-4
- Min.Order: 10 Gram
- Payment Terms: T/T,MoneyGram
- Product Details
Keywords
- Nsi-189
- 1270138-41-4
- 1270138-41-4 Nsi-189
Quick Details
- ProName: Hot Selling High Quality Nsi-189 12701...
- CasNo: 1270138-41-4
- Molecular Formula: C22H33N4O5P
- Appearance: White Crystalline Powder
- Application: It Can Be Used As Pharmaceutical Inte...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: shanghai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 10 Gram
Superiority
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
5. High quality & competitive price;
Details
| Product Name |
NSI-189 |
| CAS |
1270138-40-3 |
| MF |
C22H30N4O |
| MW |
366.4998 |
| Appearance |
White Powder |
| Structural Formula |
HOOC (CH2) 7COOH |
| Grade |
Pharma Grade |
| Usage |
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine created by Neuralstem, Inc. Research into NSI-189 has been heavily funded by the Defense Advanced Research Projects Agency (DARPA) and theNational Institutes of Health (NIH). |
Description:
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro. In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).
Application:
NSI-189 successfully completed a phase I clinical trial for MDD in 2011, where it was administered to 41 healthy volunteers. A phase Ib clinical trial for treating MDD in 24 patients started in 2012 and completed in July 2014, with results published in December 2015. Neuralstem is now preparing to initiate phase II clinical studies for MDD in the first quarter of 2016, with results expected in the second half of 2017. In the two clinical studies conducted thus far, NSI-189 has shown statistically significant effectiveness in reducing depressive symptoms, has been found to be safe and well-tolerated (with no major adverse effects observed), and has been found to improve cognitive deficits in depressed patients. In addition to MDD, Neuralstem intends to pursue clinical development of NSI-189 for a variety of other neurological conditions, including traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging.
Specification:
| Items of Analysis | Requirements | Results |
| Appearance | Off-white to white powder | Conforms |
| Loss on drying | ≤1.0% | 0.6% |
| Heavy metal | ≤10ppm | Conforms |
| Water | ≤0.5% | 0.3% |
| Purity(HPLC) | ≥99% | 99.47% |
| Residue on ingnition | ≤0.3% | 0.05% |
| Conclusion | The product conforms to in House Standard | |
| Packing | Pack in two layers plastic-bag. | |
| Storage | Store in a well-closed place with constant low temperature and no direct sun light. | |
| Shelf life |
2 years when properly stored. |
|
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.
4. Warm after-sale service Any of your question would be solved for the first as soon as possible.
Hot selling high quality NSI-189 1270138-41-4 with reasonable price and fast delivery !!!