Pharmaceutical Intermediate Mosapride Citrate for Promoting Digestion CAS 112885-42-4 CAS NO.112885-42-4

Min.Order: 100 Gram
Payment Terms: T/T,

Product Details

Keywords

112885-42-4
Mosapride Citrate
C27H37ClFN3O12

Quick Details

ProName: Pharmaceutical Intermediate Mosapride ...
CasNo: 112885-42-4
Molecular Formula: C27H37ClFN3O12
Appearance: powder
Application: Pharmaceutical Intermediate
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

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Pharmaceutical Intermediate Mosapride Citrate for Promoting Digestion CAS 112885-42-4

Quick Detail:

Product Name	Mosapride Citrate
Synonym	4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-benzamide 2-hydroxy-1,2,3-propanetricarboxylate;Gasmotin;4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl) methyl]morpholin-2-yl]methyl] benzamide;4-azanyl-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl) methyl]morpholin-2-yl]methyl]benzamide;
CAS NO	112885-42-4
MF	C27H37ClFN3O12
MW	650.05
EINECS	1806241-263-5
Purity	99%
Appearance	White Powder
Melting Point	143-145°C
Usage	Promote Digestion

Description:

Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. The major active metabolite of mosapride, known as M1, additionally acts as a 5HT3 antagonist,[1] which accelerates gastric emptying throughout the whole of the gastrointestinal tract in humans,[2] and is used for the treatment of gastritis, gastroesophageal reflux disease, functional dyspepsia[3] and irritable bowel syndrome.[4] It is recommended to be taken on an empty stomach (i.e. at least one hour before food or two hours after food).[5]

In addition to its prokinetic properties, mosapride also exerts anti-inflammatory effects on the gastrointestinal tract which may contribute to some of its therapeutic effects.[6] Mosapride also promotes neurogenesis in the gastrointestinal tract which may prove useful in certain bowel disorders.[7][8] The neurogenesis is due to mosapride's effect on the 5-HT4 receptor where it acts as an agonist.[9]

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