Powder Nolvadex Tamoxifen Citrate Anti Estrogen Steroids CAS 10540-29-1 CAS NO.10540-29-1

Powder Nolvadex Tamoxifen Citrate Anti Estrogen Steroids CAS 10540-29-1

 
 

Quick Details:

 

• Tamoxifen
• Alias:Nolvadex-D;tamoxifen(z)
• Purity : 99%min
• CAS Registry Number:  10540-29-1
• Einecs No: 234-118-0
• Molecular formula: C26H29NO
• Molecular weight:371.51
• Grade : Pharmaceutical Grade
• Storage: Shading, confined preservation
• Usage : pharmaceutical material, etc 

  
 

 

Description:

 

 

1 . This product is most often referred to as "Nolvadex" by bodybuilders. Nolvadex is not a steroid, rather

 

a selective estrogen blocker. While Nolvadex doesn't prevent the buildup of estrogen in the body, it does

 

prevent it from acting on certain receptors, most notably, those located in the nipples. This has obvious

 

benefits to bodybuilders, because this is the area in which "gyno" occurs during the use of aromatizing

 

steroids such as testosterone.

 

2 . Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues,

 

and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very

 

similar in structure. It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen

 

from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do

 

nothing.
 

 

3 . The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight

 

reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Nolvadex.
 

Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect

 

exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that

 

no one has noticed any such thing from Clomid, which has the same activity profile.
 

The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less,

 

since weight gain is less, thus reinforcing the bias.,

 

 

 

 

Specifications :

 

 

 

Product name	Tamoxifen citrate (Nolvadex)
Appearance	White crystalline powder
Identification	IR , UV conform	Conform
Loss on drying	≤0.5ml	0.21ml
Residue on ignition	Not more than 0.2%	0.07ml
Iron	Not more than 0.005%	0.0017%
Heavy metals	Not more than 0.001%	0.0006%
Related substances	Total: Not more than 1.0% Individual: Not more than 0.5%	0.35% 0.13%
E-isomer	Not more than 0.3%	0.18%
Organic volatile impurities	Conforms	Conforms
Assay	99.0~101.0%	99.6%

 

 

 

Applications:  
 

 

1 . Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-

 

hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be

 

characterized as a Selective estrogen-receptor modulator. Tamoxifen is the usual endocrine (anti-

 

estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a

 

standard in post-menopausal women although aromatase inhibitors are also frequently used in that

 

setting.

 

 

2 . Tamoxifen is used to treat infertility in women with anovulatory disorders. A dose of 10–40 mg per day

 

is administered in days 3–7 of a woman's cycle.In addition, a rare condition occasionally treated with

 

tamoxifen is retroperitoneal fibrosis.

 

 

3 . Tamoxifen is currently used for the treatment of both early and advanced ER+ (estrogen receptor

 

positive) breast cancer in pre- and post-menopausal women.Additionally, it is the most common hormone

 

treatment for male breast cancer.It is also approved by the FDA for the prevention of breast cancer in

 

women at high risk of developing the disease.It has been further approved for the reduction of

 

contralateral (in the opposite breast) cancer.

 

 

4 . Tamoxifen also increase the risk of adverse side effects. Some cases of lower-limb lymphedema have

 

been associated with the use of tamoxifen, due to the blood clots and deep vein thrombosis (DVT) that

 

can be caused by this medication. Resolution of the blood clots or DVT is needed before lymphedema

 

treatment can be initiated.