99% Purity Pharmaceutical Grade Acyclovir Powder CAS 59277-89-3 for Antiviral
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Product Name: |
Acyclovir |
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Synonyms: |
1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on;aciclovirum(latin);aclovir;Acycolguanosine;bw248u;vipral;virorax |
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CAS: |
59277-89-3 |
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MF: |
C8H11N5O3 |
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MW: |
225.2 |
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EINECS: |
261-685-1 |
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Product Categories: |
PHARMACEUTICALS;Active Pharmaceutical Ingredients;Purine;Nucleotides and Nucleosides;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Amines;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;API's;Valacyclovir Hydrochloride Monohydrate;Antiviral;Herpes Viruses;Anti-virals;THALOMID;inhibitor |
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Mol File: |
59277-89-3.mol |
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Acyclovir Chemical Properties |
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Melting point |
256-257°C |
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Boiling point |
366.71°C (rough estimate) |
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density |
1.3654 (rough estimate) |
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refractive index |
1.8000 (estimate) |
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storage temp. |
−20°C |
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solubility |
H2O: 0.7 mg/mL |
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form |
powder |
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pka |
pKa 2.27 (Uncertain);9.25 (Uncertain) |
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color |
white |
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Water Solubility |
Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO |
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Merck |
14,146 |
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Stability: |
Stable. Incompatible with strong oxidizing agents. |
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CAS DataBase Reference |
59277-89-3(CAS DataBase Reference) |
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Hazard Codes |
Xi,Xn |
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Risk Statements |
36/37/38-40-20/21/22 |
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Safety Statements |
22-24/25-36-26-23 |
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WGK Germany |
2 |
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RTECS |
UP0791400 |
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HazardClass |
IRRITANT |
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Hazardous Substances Data |
59277-89-3(Hazardous Substances Data) |
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Toxicity |
LD50 in mice (mg/kg): >10,000 orally; 1000 i.p. (Schaeffer) |
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Acyclovir Usage And Synthesis |
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Chemical Properties |
white to light yellow crystal powder |
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Uses |
hypnotic |
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Uses |
Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral |
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Definition |
ChEBI: An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. |
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Biological Activity |
Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy). |
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Acyclovir Preparation Products And Raw materials |
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Raw materials |
Sodium nitrite-->p-Toluenesulfonic acid-->METHYLAMINE-->6-Hydroxypurine-->Adenine-->5'-Guanylic acid-->Guanine-->2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrate-->TRIMETHYLSILANE-->1,4-DIACETOXYBUTANE-->6-Methoxyguanine-->9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine |
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Tag:Acyclovir(59277-89-3) Related Product Information |
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99% Purity Pharmaceutical Grade Acyclovir Powder CAS 59277-89-3 for Antiviral
China (Mainland)
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