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Albuterol Sulfate CAS 51022-70-9 Bronchial Asthma White Powder All Inhibitors CAS NO.51022-70-9
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Keywords
- 51022-70-9
- Albuterol Sulfate
- Salbutamol sulfate
Quick Details
- ProName: Albuterol Sulfate CAS 51022-70-9 Bronc...
- CasNo: 51022-70-9
- Molecular Formula: 2(C13H21NO3).H2O4S
- Appearance: white crystalline solid
- Application: Pharmaceutical Raw Materials; Pharmace...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 10 Gram
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Details
Albuterol Sulfate CAS 51022-70-9 Bronchial Asthma White Powder All Inhibitors
Quick detail
| Name: | Albuterol sulfate |
| CAS No.: | 51022-70-9 |
| Formula: | 2(C13H21NO3).H2O4S |
| Molecular Weight: | 576.70 |
| Synonyms: | .alpha.1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-.alpha., .alpha.-diol sulfate (2:1) salt;Bronchospray;(+-)-Salbutamol sulfate;Albuterol sulfate (USP);1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylamino)ethanol sulfate;Loftan;Epaq;1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, sulfate (2:1) (salt) (9CI);Ventolin HFA;Emican;Salbutamol hemisulfate;Broncho Inhalat;Huma-Salmol;Albuterol sulfate / Salbutamol sulfate; |
| EINECS: | 256-916-8 |
| Melting Point: | 180 °C |
| Boiling Point: | 433.5 °C at 760 mmHg |
| Flash Point: | 159.5 °C |
| Solubility: | soluble in water |
| Appearance: | white crystalline solid |
Albuterol Sulfate Description
Albuterol Sulfate/Salbutamol/Ventolin powders/Proventil powders/CAS No: 51022-70-9
It is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.
Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.
Albuterol Sulfate DOSAGE AND ADMINISTRATION
For treatment of acute episodes of bronchospasm or prevention of asthmatic symptoms, the usual dosage for adults and children 4 years of age and older is two inhalations repeated every 4 to 6 hours. More frequent administration or a larger number of inhalations is not recommended. In some patients, one inhalation every 4 hours may be sufficient.
Each actuation of PROVENTIL® HFA Inhalation Aerosol delivers 108 mcg of albuterol sulfate (equivalent to 90 mcg of albuterol base) from the mouthpiece. It is recommended to prime the inhaler before using for the first time and in cases where the inhaler has not been used for more than 2 weeks by releasing four “test sprays” into the air, away from the face.
Possible Side Effects of Albuterol Sulfate
Call your doctor at once if you have a serious side effect such as:
- bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
- chest pain and fast, pounding, or uneven heart beats;
- tremor, nervousness;
- low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp...
Specifications:
| Test Items | Specification | Test Results | |
| Appearance | white oralmost white,crystalline powder | Conform | |
| Solubility | Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride. | Conform | |
| Identification | A | The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64. | Conform |
| B | Infraed absorption spectrophotometry. | Conform | |
| C | Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. | Conform | |
| D | An orange-red color develop in methylene chloride layer. | Conform | |
| E | It geves reaction (a) of sulphates. | Conform | |
| Appearance of solution | Solution S is clear and not more intensely coloured than reference solution in BY6. | Conform | |
| Optical rotation | ﹣0.10° to +0.10°determined on solution S. | +0.01° | |
| Acidity or alkalinity | NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. | Conform | |
| Related substances | Impurity J ≤0.20% | Conform | |
| Any other impurity ≤0.30% | Conform | ||
| Total impurity ≤1.0% | Conform | ||
| Boron | ≤50ppm | Conform | |
| Sulphated ash | ≤0.10% | 0.06% | |
| Loss on drying | ≤0.5% | 0.30% | |
| Assay(on dried basis) | 98.0~101.0% | 98.8% | |
| Conclusion |
The test results above BP2009 |
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