7, 8-Dihydroxyflavone CAS NO.38183-03-8

Hubei Langyou International Trading Co., Ltd is a renowned pharmaceutical manufacturer. We specializing in the production of research and development of pharmaceutical intermediates, this kind of products with high quality price concessions, welcomed the new and old customers advisory purchase, companies invest large fund and brain research fine chemical r&d department,biochemical,  pharmaceutical and intermediate products to meet the demand of the market. High level research team,advanced equipment and good scientific atmosphere ensure the quality .

1.Reasonable and competitive price. Provide the best and professional service.Provide the best and professional service is our purpose.

2. Reliable shipping way.Door to door service, guarantee 100% delivery for you.

We have our own shipping agent in each country,we have special lines to your country, you no need do anything.

Will finish all the customs clearance at our side, customers are without any customs issues,door to door delivery.

3.To below countries, we are very  familiar and regular.

UK,USA,Canada,Russia,Ukraine,Kazakhstan,Belarus,Germany,Poland,Sweden,the Netherlands, Australia,Spain,Mexico,Poland  and so on. All are without problems.

 Factory Directly Supply  7, 8-Dihydroxyflavone CAS: 38183-03-8

7,8-Dihydroxyflavone 7,8-DHF

CAS No.: 38183-03-8

Formula: C15H10O4

EINECS: 253-812-4

Type: Pharmaceutical Intermediates

Appearance: Powder

Quality: Medical Grade

MW： 254.24

Colour light yellow powder

7,8-Dihydroxyflavone Chemical Properties

Melting point 243-246°C

Boiling point 494.4±45.0 °C(Predicted)

density 1.443±0.06 g/cm3(Predicted)

FEMA 4830 | 7,8-DIHYDROXYFLAVONE

storage temp. Inert atmosphere,Room Temperature

solubility DMSO: soluble24mg/mL

form solid

pka 6.86±0.40(Predicted)

color Yellow or tan

Transport Package 1kg

Specification 99%

Origin China

Production Capacity

5000kg/Month

Type: Pharmaceutical Intermediates

Appearance: Powder

Quality: Refined

Description 7,8-Dihydroxyflavone(7,8-DHF) is a naturally occurring flavone found in the tree Godmania aesculifolia. It is a selective tyrosine kinase receptor B(TrkB) agonist that has neurotrophic effects in various neurological diseases such as stroke and Parkinson's disease. 7,8-Dihydroxyflavone binds to the TrkB receptors in a similar way to BDNF, or brain derived neurotrophic factor. When the TrkB receptor is activated, neuroprotective and neurogenetive effects occur in neurons, which tend to affect the dendrites. Dendrites are what reach out from the neurons into the synapse to participate in signaling with other neurons. 7,8-DHF has been shown to promote the growth of these dendrites, and to help restore communication between neurons in animal models.

Chemical Properties White crystalline powder or Yellow Solid, soluble in methanol, ethanol, DMSO and other organic solvents, from the dried root of Pulsatilla chinensis (Bge.) Regel.

Uses 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheimer''s disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. It has recently been shown to counteract the inhibition of NMDA receptor caused by lead poisoning and confer protective effects in live rats