Pharmaceutical Raw Material Cinacalcet Hydrochloride (CAS 364782-34-3) CAS NO.364782-34-3

Min.Order: 100 Gram
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Keywords

364782-34-3
Cinacalcet Hydrochloride
Cinacalcet hcl

Quick Details

ProName: Pharmaceutical Raw Material Cinacalcet...
CasNo: 364782-34-3
Molecular Formula: C22H23ClF3N
Appearance: White or off-white crystalline powder
Application: in the treatment of PARATHYROID DISEAS...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

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Pharmaceutical Raw Material Cinacalcet Hydrochloride (CAS 364782-34-3)

Product Description

Cinacalcet hydrochloride Description
Cinacalcet hydrochloride is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in the treatment of PARATHYROID DISEASES.

Cinacalcet Hydrochloride is the orally bioavailable hydrochloride salt of the calcimimetic cinacalcet. Cinacalcet increases the sensitivity of calcium-sensing receptors on chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone (PTH) secretion. A reduction in PTH levels inhibits osteoclast activity, which may result in a decrease in cortical bone turnover and bone fibrosis, and normalization of serum calcium and phosphorus levels. In addition, by reducing PTH levels, cinacalcet may reduce PSA levels; PTH appears to raise PSA levels and may increase prostate cancer cell growth.

Cinacalcet hydrochloride
CAS:364782-34-3
Chemical name:N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Appearance	White or off-white crystalline powder
Identification	IR/HPLC
Solubility	Slightly soluble in water, soluble in MeOH
Melting point	180-181°C
Loss on drying	≤0.5%
Heavy metals	≤20ppm
Residue on ignition	≤0.1%
Related substance	CF2H-Cinacalcet≤0.7% Any other impurity≤0.25%
e.e.(HPLC)	≥99.0%
Purity(HPLC)	≥99.0%

Pharmaceutical Raw Material Cinacalcet Hydrochloride (CAS 364782-34-3)

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