- Product Details
Keywords
- 34552-83-5
- Loperamide Hydrochloride
- Loperamide Hcl
Quick Details
- ProName: Raw Material Loperamide Hydrochloride ...
- CasNo: 34552-83-5
- Molecular Formula: C29H34Cl2N2O2
- Appearance: Crystals
- Application: Pharmaceutical Raw Materials; Pharmace...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 10 Gram
Superiority
Our Adwantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
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Details
Pharmaceutical Raw Powder Loperamide Hydrochloride 34552-83-5 Gastrointestinal Drugs
Quick detail
Loperamide hydrochloride | ||
CAS No.: | 34552-83-5 | |
Synonyms: | loperamide HCl: Lopemid; LoperaMide Hydrochloride; Imodium; 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide, hydrochloride; Suprasec; Loperamide hydrochloride; Loperyl; Fortasec; Loperamide HCl; Dissenten; Lopemin; | |
Formula: | C29H34Cl2N2O2 | |
Exact Mass: | 512.20000 | |
Molecular Weight: | 513.49800 | |
PSA: | 43.78000 | |
LogP: | 5.82790 | |
Appearance | Crystals, practically insoluble in water | |
Melting Point: | 223-225ºC | |
Boiling Point: | 647.2ºC at 760 mmHg | |
Flash Point: | 345.2ºC |
Safety Info | |
RTECS: | TM4960000 |
Hazard Class: | 6.1(b) |
Safety Statements: | S45 |
Packing Group: | III |
WGK Germany: | 3 |
RIDADR: | UN 2811 |
Risk Statements: | R25 |
Hazard Codes: | T |
Description
Loperamide is the generic form of the brand-name drug Imodium, a medication used to treat diarrhea.
Imodium works by slowing down the movement of the gut. This decreases the number of bowel movements and makes stool less watery.
Imodium may also be used to decrease the amount of discharge in patients who have undergone an ileostomy(a procedure to move waste out of the body when the colon or rectum is not working properly) or to treat people with inflammatory bowel disease (IBD).
Usage
Usage | Labeled Loperamide, which is used as an antidiarrheal |
Usage | Ca channel blocker |
Biological Activity | High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels. |
How it Works
Loperamide hydrochloride causes the activity within the intestines to slow down. It also alters the movement of both electrolytes and water through the bowels. According to Drugs.com, it may take as many as 48 hours for the medicine to control diarrhea symptoms.
Side Effects
- Loperamide hydrochloride often causes dry mouth, which can be alleviated by chewing gum or eating hard candy. Other side effects include constipation, sleepiness and dizziness.
- Some individuals may have an allergic reaction to loperamide hydrochloride, which may manifest as a severe rash, fever, sore throat or continued diarrhea
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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