top quality Glipizide cas#29094-61-9 CAS NO.29094-61-9

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Glipizide

English Name: Glipizide CAS No. 29094-61-9

Product Category: Pharmaceutical Raw Materials

Product content: 99% or more (%)

Quality standard: USP

Packaging Specification: 25KG

Functional Indications: This product is mainly used for mild to moderate non-insulin dependent patients who can not achieve good results by diet control alone.

Appearance: White crystalline or crystalline powder

CAS:29094-61-9 Chemical name: 1-cyclohexyl-3-{4-[2-(5-methylpyrazine-2-amide) -ethyl] phenylsulfonyl} urea formula: C21H27N5O4S molecular weight: 445.54 content: 99% specification: appearance: white or white crystalline powder indication: this product is mainly used for diet control treatment alone failed to achieve good results Mild to moderate non-insulin-dependent patients; in the past, insulin was used, but the daily requirement was less than 30-40 units; for asymptomatic patients, there was still significant hyperglycemia on the basis of dietary control; for insulin-resistant patients, the pharmacological effect of this product was added: glipizide was orally lowered as a second-generation sulfonylurea. Drugs for blood sugar. It mainly promotes insulin secretion by islet beta cells, especially by glucose-stimulated insulin beta cells. It also enhances insulin action, which effectively reduces blood sugar concentration and glycosylated hemoglobin. It can also improve hyperlipidemia, reduce triglyceride and cholesterol levels, and increase high-density lipoprotein cholesterol. The ratio of total cholesterol can also inhibit platelet aggregation and promote fibrinolysis, which may have a preventive and therapeutic effect on vascular diseases. To promote insulin secretion of ** islet B cells, the prerequisite is that islet B cells also have certain function of synthesizing and secreting insulin; to inhibit hepatic glycogen decomposition and glycogen allogenesis by increasing insulin level in portal vein or directly acting on liver; to reduce hepatic glycogen production and output; and to increase extrapancreatic group. The susceptibility of tissue to insulin and the utilization of sugar (possibly mainly through post-receptor effect), therefore, the overall effect is fast absorption of pharmacokinetics. After oral administration, the blood concentration reaches its peak at 1-2.5 hours, lasting for 24 hours, and T1/2 is 2.5-4 hours. It was mainly inactivated by liver metabolism. 97% of them were discharged from the body on the 1st day and 100% on the 2nd day. Packaging Specification: 25kg/drum

Chinese alias 1-cyclohexyl-3-{4-[2-(5-methylpyrazine-2-amide) -ethyl] phenylsulfonyl} urea; glipizide; glimethazine; pyridylcyclohexyl urea

CAS RN 29094-61-9

EINECS 249-427-6

Molecular formula C21H33N5O4S

Molecular weight 451.5828

Physicochemical Properties Appearance: White or quasi-white crystalline powder

Used as a hypoglycemic drug for non-insulin dependent diabetes mellitus (type II)