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Cinnamonitrile Manufacturer 1885-38-7 Antibacterial Effect CAS NO.1885-38-7
- Min.Order: 10 Gram
- Payment Terms: T/T,
- Product Details
Keywords
- 99% Cinnamonitrile
- Cinnamonitrile Manufacturer
- Antibacterial Effect
Quick Details
- ProName: Cinnamonitrile Manufacturer 1885-38-7 ...
- CasNo: 1885-38-7
- Molecular Formula: C9H7N
- Appearance: White Powder
- Application: It Can Be Used As Pharmaceutical Inte...
- DeliveryTime: 2-4 days after confirming your payment...
- PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
- Port: Wuhan
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: Store in sealed containers at cool & d...
- Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
- LimitNum: 10 Gram
Superiority
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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Details
| Cinnamonitrile Basic information |
| Product Name: | Cinnamonitrile |
| Synonyms: | (2E)-3-Phenyl-2-propenenitrile;(e)-2-propenenitril;(E)3-Phenylacrylonitrile;(E)-3-Phenylprop-2-enenitrile;(E)-3-Phenylpropenenitrile;(E)-Cinnamonitrile;3-phenyl-,(E)-2-Propenenitrile;3-trans-phenyl-acrylonitrile |
| CAS: | 1885-38-7 |
| MF: | C9H7N |
| MW: | 129.16 |
| EINECS: | 217-552-5 |
| Product Categories: | Miscellaneous;Heterocyclic Compounds;Aromatics;Inhibitors;Building Blocks;C8 to C9;Chemical Synthesis;Cyanides/Nitriles;Nitrogen Compounds;Organic Building Blocks |
| Mol File: | 1885-38-7.mol |
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| Cinnamonitrile Chemical Properties |
| Melting point | 18-20 °C(lit.) |
| Boiling point | 254-255 °C(lit.) |
| density | 1.028 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Fp | >230 °F |
| storage temp. | Store at <= 20°C. |
| form | Liquid |
| color | Clear colorless to yellow |
| Water Solubility | insoluble |
| Sensitive | Air & Light Sensitive |
| CAS DataBase Reference | 1885-38-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Propenenitrile, 3-phenyl-, (E)-(1885-38-7) |
| EPA Substance Registry System | 2-Propenenitrile, 3-phenyl-, (2E)-(1885-38-7) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| RTECS | UD1440000 |
| F | 9 |
| TSCA | Yes |
| HS Code | 29269095 |
| Cinnamonitrile Usage And Synthesis |
| Flavors | Cinnamonitrile is also known as styrene cyanide, is an excellent synthetic spice,it has a strong spicy aroma like cinnamon and floral nuances, colorless or pale yellow viscous liquid, it is chemically stable, light, heat or acid, alkaline etching can not make it change. There are no toxic side effects on the human body, there is no stimulation in contact with skin ,there are no allergic reactions, compared with cinnamic aldehyde, cinnamonitrile has the stronger ability through the hair, the aroma is strong and lasts for a long time, potential skin irritation and toxicity are smaller than cinnamic aldehyde,it is the ideal substitute for cinnamon oil and cinnamic aldehyde,it can be used in daily chemical flavor formula,it is mainly used for soap flavor and fragrance detergent formulations, the amount is less than 2%. IFRA has no restrictions. Since cinnamonitrile has a unique chemical structure,it can occur Friedel, addition, reduction, hydrolysis reactions,it is also widely be used in the pharmaceutical, fine chemical industry . According to the information provided by RIFM, acute toxicity data of cinnamonitrile: oral LD504.15g/kg (rat), skin test LD50> 5g/kg (rabbit). Cinnamonitrile can be made by condensation of acetonitrile with benzaldehyde in the presence of potassium hydroxide solution ; or it can be made by the first transformation of cinnamaldehyde into oxime, then by the dehydration following. |
| Chemical properties | Light transparent pale yellow liquid with a strong, warm spicy fragrance. |
| Antibacterial effects | Nanjing University Department of Biology and the Institute of Hydrobiology of the Chinese Academy of Sciences teachers measured the inhibitory effects of plant pathogens Altornaria tenuis Nees and Rhizopus nigricans on their own separate identification , skin addiction germs Epidermophyton floccosum, Trichophytoa gypsoum, Trichophyton rubrum, Microsporum gypseum, as well as 22 kinds of mold ( 18 kinds of common food, fruits and other mold rot fungus, four kinds of human shallow filamentous fungus), the results show that cinnamonitrile has a high nitrile antimicrobial effect,it has the role of antibiotics, but it is not an antibiotic,its mold inhibition effect is good, it has broad antibacterial spectrum , and anthelmintic effect. Experiments show that the breeding of bacteria in the production process needs folic acid to participate in , cinnamonitrile structure is similar to PABA, they are competitive in binding with dihydrofolate synthase, which inhibits the activity of dihydrofolate synthase, impeding dihydrofolate synthesis, thus affecting the synthesis of folic acid, inhibiting bacterial growth propagation; and it can interfere with the synthesis of some bacteria, and the synthesis of the enzyme needed for cell division to inhibit and impact the synthesis of bacterial RNA , which reduces the permeability of the cell membrane thus affects the normal metabolism of bacteria, resulting in death, so bactericidal effect are more thorough . What is more amazing is that the human body does not produce Cinnamonitrile dependence, it can eliminate bacteria tribes, but it will not break the constraints relationship between bacteria and thus does not produce resistance. Cinnamonitrile itself is a spice, there are no toxic side effects on the human body, in contact with skin no stimulation, no allergic reactions. Experts said excitedly,that with deepening study of the cinnamonitrile antibacterial aspect , cinnamonitrile is expected to completely replace antibiotics, and become the "Terminator"of antibiotics. |
| Application |
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| Preparation | Cinnamic aldehyde reacts with hydroxylamine hydrochloride in the presence of pyridine by the addition-elimination reaction to produce aldehyde oxime, then it boils with toluene azeotropic and after dehydration to generate cinnamonitrile. |
| Chemical Properties | clear colourless to yellow liquid |
| Uses | The parent compound whose derivatives can be applied as corrosion inhibitors for API J55 steel. |