Hot Sale beta nicotinamide adenine dinucleotide phosphate/ NADP with best price 1184-16-3 CAS NO.1184-16-3 CAS NO.1184-16-3

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Product Description 

Nicotinamide adenine dinucleotide, abbreviated NADh+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.

In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is, therefore, found in two forms in cells: NAD+ is an oxidizing agent – it accepts electrons from other molecules and becomes reduced. This reaction forms NADH,   (Nicotinamide adenine dinucleotide) which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.

In organisms, NAD+ can be synthesized from simple building-blocks (de novo) from the amino acids tryptophan or aspartic acid. In an alternative fashion, more complex components of the coenzymes are taken up from food as the vitamin called niacin. Similar compounds are released by reactions that break down the structure of NAD+. These preformed components then pass through a salvage pathway that recycles them back into the active form. Some NAD+ is also converted into nicotinamide adenine dinucleotide phosphate (NADP+); the chemistry of this related coenzyme is similar to that of NAD+, but it has different roles in metabolism. 

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•About us

Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.

We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.

We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.

We have won ISO 9001:2000 certification. and our quality control Dept. is engaged in the activities for securing stable product quality. and it is responsible for the guidance with and the management of quality assurance activities of the entire company in order to ascertain that our manufacturing activity could be carried out in compliance with the related laws, regulations and ISO standard.

•about Noopept

Description:

Nootropic drugs are described as "Smart Drugs" because, as a whole, this drug category can have an enhancing effect in the areas of memory, focus, cognition, and neurological deficits. The bulk of these drugs have proven to improve conditions like dementia, Alzheimer's disease, and certain types of brain traumas. Noopept is one such nootropic. Noopept is a brand name for a chemical called N-phenylacetyl-L-prolylglycine ethyl ester, which is the synthetic alternative to Piracetam. In order to receive the greatest benefit the required dosage of Noopept is much lower than Piracetam. For example, 4800 mg of piracetam is equated to a daily dosage of Noopept at only 15-30 mg. After administration, Noopept appears to provide a neuro protective effect; however, researchers have yet to explain exactly why this neuro protective element occurs

Application:

it has been determined that Noopept was beneficial in restoring cognition in regard to Alzheimer's disease. It has, also, shown to prevent free radicals and pro-inflammatory cytokines accumulation, ionic imbalance, neurotrophin deficit and excitotoxicity. (Ostrovskaya, & et. al, 2014). However, as yet, the neuro protective qualities identified apparently do not affect brains that are not impaired; the uninjured daily user may experience little or no effect from Noopept (Frank, 2014). The effects of Noopept do appear to vary from user to user. Some experience a minute change in their memory and cognitive abilities, and others may experience a huge increase in memory ability and capacity to recall small details.

The short and long-term effects of Noopept use have proven to be beneficial and positive. The increased capacity of memory, attention span, and overall cognition is improved. According to experts, after tests conducted on rabbits, explain that there have been no toxic, allergic, or direct health risks associated with this nootropic.