Losartan Medication Anti-Hypertensive Drugs 114798-26-4 Losartan Medicine CAS NO.114798-26-4

Min.Order: 100 Gram
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Keywords

114798-26-4
Losartan
Pharmaceuticals raw material

Quick Details

ProName: Losartan Medication Anti-Hypertensive ...
CasNo: 114798-26-4
Molecular Formula: C22H23ClN6O
Appearance: White powder
Application: used alone or with other agents to tre...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 20000 Kilogram/Day
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 100 Gram

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Details

Losartan Medication Anti-Hypertensive Drugs 114798-26-4 Losartan Medicine

Name	Losartan
Synonyms	(2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
Molecular Formula	C₂₂H₂₃ClN₆O
Molecular Weight	422.9106
CAS Registry Number	114798-26-4

Description:

Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.

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