99% High Purity CAS 1143-38-0 Dithranol anthralin CAS NO.1143-38-0

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99% High Purity CAS 1143-38-0 Dithranol anthralin

ANTHRALIN Basic information

Product Name:	ANTHRALIN
Synonyms:	DITHRANOL;DITHRANOL, ANTHRALIN;ANTHRALIN;1,8-DIHYDROXY-10H-ANTHRACEN-9-ONE;1,8-DIHYDROXY-9(10H)-ANTHRACENONE;1,8-DIHYDROXYANTHRONE;1,8,9-ANTHRACENETRIOL;1,8-dihydroxy-9(10h)-anthracenon
CAS:	1143-38-0
MF:	C14H10O3
MW:	226.23
EINECS:	214-538-0
Product Categories:	Aromatic Phenols;Intermediates & Fine Chemicals;Pharmaceuticals;ANTRADERM;Skin drugs, treatment of psoriasis;API
Mol File:	1143-38-0.mol

ANTHRALIN Chemical Properties

Melting point	178-181 °C(lit.)
storage temp.	2-8°C
solubility	Practically insoluble in water, soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
Water Solubility	Insoluble in water. Soluble in acetic acid, chloroform (20 mg/mL), acetone, benzene, solutions of alkali hydroxides, fixed oil. Slightly soluble in 95% ethanol, alcohol, ether, and glacial acetic acid.
Merck	14,684
BRN	2054360
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	1143-38-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,T
Risk Statements	36/37/38-45
Safety Statements	26-53-45
WGK Germany	3
RTECS	CB8927000

MSDS Information

Provider	Language
SigmaAldrich	English

ANTHRALIN Usage And Synthesis

Chemical Properties	Yellow Crystalline Solid
Uses	Antipsoriatic
Uses	Dithranol, a potential anti-psoriasis medication, may be used to study its safety, efficacy, metabolism and pharmacological profile. Dithranol may be used to study is physicochemical properties, as a reference compound and to develop effective drug delivery vehicles. Dithranol may be used as a matrix for matrix assisted laser desorption/ionization imaging on a Fourier transform ion cyclotron resonance mass spectrometer.
Definition	ChEBI: An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.
Brand name	Anthra-Derm (Dermik); DrithoCreme (Dermik); Drithoscalp (Dermik); Lasan (Stiefel).
General Description	Lemon yellow leaflets or plates or an orange powder. Melting point 176-181°C. No odor or taste. Insoluble in water. Moderately toxic by ingestion, inhalation and skin absorption. Used as a treatment for psoriasis.
Air & Water Reactions	Unstable in air when in alkaline solution. Insoluble in water.
Reactivity Profile	ANTHRALIN reacts as a weak acid. Soluble in aqueous bases. May react with strong oxidizing agents. May be sensitive to light and moisture .
Hazard	Very irritating. Do not use on scalp or near eyes.
Fire Hazard	Flash point data are not available for ANTHRALIN; however, ANTHRALIN is probably combustible.

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99% High Purity CAS 1143-38-0 Dithranol anthralin