API-Pioglitazone HCl, High Purity CAS 112529-15-4 Pioglitazone Hydrochloride CAS NO.112529-15-4

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Keywords

Pioglitazone Hydrochloride
112529-15-4
112529-15-4 Pioglitazone Hydrochloride

Quick Details

ProName: API-Pioglitazone HCl, High Purity CAS ...
CasNo: 112529-15-4
Molecular Formula: C19H21ClN2O3S
Appearance: White Crystalline Powder
Application: It Can Be Used As Pharmaceutical Inte...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: shanghai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

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Details

API-Pioglitazone HCl, High purity cas 112529-15-4 Pioglitazone Hydrochloride

Product Name: Pioditazone Hydrochloride

Synonyms:Pioditazone hydrochloride;5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedionehydrochloride;AD-4833;pioglitazone hydrochioride;PIODLITAZONE HYDROCHLORIC;5-{4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL}-THIAZOLIDINE-2,4-DIONE HCL;5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-;5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride

CAS:112529-15-4
MF:C19H21ClN2O3S
MW:392.9
Product Categories:Active Pharmaceutical Ingredients;Antidiabetic;
Diabetes;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API's;Pioglitazone;Inhibitor;API;Cardiovascular Series
Melting point: 193-194°C
Storage temp.: Desiccate at RT
Chemical Properties: Colourless Prisms
Uses: euglycemic agent
Uses: Used as an antidiabetic .

Desscription:

1. Pioglitazone hydrochloride is used for the treatment of diabetes mellitus type 2 either alone or in combination with a sulfonylurea, m in, or insulin.There was, however, no statistically significant difference in the main outcomes studied.

2. Pioglitazone hydrochloride has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.Chemical Properties Colourless Prisms

3.Pioglitazone is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results.

4.Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events. Pioglitazone has been found to be associated with bladder tumors and has been withdrawn in some countries.

Medical Uses:

Pioglitazone is used to lower blood glucose levels in the treatment of diabetes mellitus type 2 (T2DM) either alone or in combination with a sulfonylurea, metformin, or insulin.The main study that looked at the medication, however, found no statistically significant difference in the main cardiovascular outcomes that were looked at.

The secondary outcome of death from all causes, myocardial infarction, and stroke were lower. Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.

specification:

Name	Pioglitazone Hydrochloride
Batch No.	160301
Mfg.Date	2016/03/03	Analysis Date	2016/03/22
Retest Date	2018/03/06	Quantity	80kg

Item		Acceptance criteria	Result
Appearance		White to off-white powder	White powder
Identifications	IR	The IR absorption spectrum of the sample is corresponding to that of the reference standard.	Complies
	Chloride	Positive	Complies
	HPLC	The retention time of the principle peak in the chromatogram of the sample corresponds to that of the reference standard.	Complies
Residue on ignition		≤0.1%	0.05%
Heavy metals		≤10ppm	<10ppm
Water		≤0.5%	0.17%
Related Substances/HPLC	Impurity A	≤0.15%	ND
	Impurity B	≤0.15%	0.07%
	Impurity C	≤0.15%	ND
	Single impurity	≤0.10%	0.01%
	Total Impurities	≤0.5%	0.09%
Assay(on dried basis)HPLC		98.0-102.0%	99.5%

Advantages:

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

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API-Pioglitazone HCl, High Purity CAS 112529-15-4 Pioglitazone Hydrochloride