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Home > Products >  High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with Best Price

High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with Best Price CAS NO.104987-11-3

  • Min.Order: 10 Gram
  • Payment Terms: T/T,
  • Product Details

Keywords

  • Tacrolimus
  • 104987-11-3
  • 104987-11-3 Tacrolimus

Quick Details

  • ProName: High Purity Tacrolimus Powder as Antib...
  • CasNo: 104987-11-3
  • Molecular Formula: C44H69NO12
  • Appearance: White Crystalline Powder
  • Application: It Can Be Used As Pharmaceutical Inte...
  • DeliveryTime: 2-4 days after confirming your payment...
  • PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
  • Port: shanghai
  • ProductionCapacity: 1000 Metric Ton/Month
  • Purity: 99%
  • Storage: Store in sealed containers at cool & d...
  • Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
  • LimitNum: 10 Gram

Superiority

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

 

5. High quality & competitive price;

 

Details

High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with best price


Basic info:


Tacrolimus
Purity: 99%
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Appearance: White powder
Lead time: 1-2 days upon receipt of payment
Delivery time: Usually 4-6 working days by air
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.



Application:


L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.



Interactions :


Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.



Dermatological Use:


As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.


It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.



 Specifications:


Test

Specification

Result

Description

A white crystalline powder

Complies

Solubility

Soluble in Methanol, Ethyl acetate and Chloroform

Complies

Water

≤3.0% 1.3%

Residue on ignition

≤0.10%

Complies

Heavy metals

<10ppm

Complies

Isomer

≤5.0% 0.56%

Individual Impurity

≤0.5% 0.33%

T otalimpurities

≤2.0% 0.43%

Assay ( on dry basis

including isomers)

≥98.0% 99.8%

Conclusion

The product conforms to the Enterprise specification.




COA:


Items of analysis Specification Results
Description a white to off-white powder white powder
By IR spectroscopy IR spectrum of sample should match with standard IR spectrum conforms
by HPLC the retention time of the major peak of the sample solution corresponds to that of the standard solution as obtained in the assay coforms
loss on drying not more than 4.0% 2.2%
residue on ignition not more than 0.2% 0.04%
heavy metals not more than 20ppm less than 20ppm
specific optical rotaion -80 ° to -90 ° -89 °
any individual impurity not more than 0.5% 0.08%
total impurity not more than 1.0% 0.25%
assay by HPLC 98.0%-102.0% 99.0%

  

Advantages:
 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
 
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
 
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
 
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.
 
4. Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

 

 

High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with Best Price

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