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Home > Products >  Glibenclamide UPS Pharmaceutical Powder CAS 10238-21-8 Glibenclamide

Glibenclamide UPS Pharmaceutical Powder CAS 10238-21-8 Glibenclamide CAS NO.10238-21-8

  • Min.Order: 100 Gram
  • Payment Terms: T/T,
  • Product Details

Keywords

  • 10238-21-8
  • Glibenclamide
  • C23H28ClN3O5S

Quick Details

  • ProName: Glibenclamide UPS Pharmaceutical Powde...
  • CasNo: 10238-21-8
  • Molecular Formula: C23H28ClN3O5S
  • Appearance: white crystalline powder
  • Application: Acarbose is an anti-diabetic drug used...
  • DeliveryTime: 2-4 days after confirming your payment...
  • PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
  • Port: Wuhan
  • ProductionCapacity: 20000 Kilogram/Day
  • Purity: 99%
  • Storage: Store in sealed containers at cool & d...
  • Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
  • LimitNum: 100 Gram

Superiority

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

 

Details

 

Glibenclamide UPS Pharmaceutical Powder CAS 10238-21-8 Glibenclamide

 

Product Description

Introduction                                            
Product Name: glibenclamide
Specification :99.5%-101%
Test method: HPLC
Appearance:White or almost white crystalline powder
CAS No.:10238-21-8

Glibenclamide COA

ITEM

STANDARD

RESULTS

Appearance

Crystalline powder

Conforms

Melting range

129°C~132°C

130.8°C-131°C

Loss on drying

≤0.5%

0.20 %

Specific rotation

-58°~-62°(C=1,in CH3OH)

-61.05°

Sulphated ash

≤0.1%

0.08 %

Heavy metals

≤10ppm

Conforms

Chlorides

≤0.02%

Conforms

Sulfates

≤0.02%

Conforms

Fluorine

14.7%~17.9%

15.2%

Residual solvent

Methanol ≤0.2%
Isopropanol ≤0.2%
Ethyl acetate≤0.2%
Chloroform ≤0.2%

0.0%
0.0%
0.0%
0.0%

Related substances
(HPLC)

Single impurity ≤0.2%
Total impurities ≤0.5%

0.05%
0.08%

Assay

≥99.5%

99.92%

Conclusion

Accordance with the reference

 


Function                                                  
Hypoglycaemic. Inhibit decomposition of glycogen and Gluconeogenesis, reduce glucoses production and output in liver;Besides, it can strengthen pancreass sensitivity to insulin and consume more sugar,reducing FPG and P2hPG. For the second-generation sulfonylurea drugs, there is a strong role in lowering blood glucose, its hypoglycemic effect than D-860 Strong 100-fold. Fasting blood glucose after treatment compared with postprandial blood glucose significantly decreased, respectively, reduced by about 35%, and 21% or less.Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high.Fall blood sugar function strong, Glyburide capsule: its role a toluene sulfonylurea urea butyl 100 times stronger. Oral 30 minutes later appeared for about 16 ~ role 24 hours. Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high. T1/2 about 10 h. Almost all by hepatic metabolism, the main metabolites hypoglycemic activity is weak. About 50% of metabolites from urine discharge, and another 50% by bile into debris. 
Glyburide piece: this product is lowering blood sugar pills. 1. Stimulate pancreatic beta cells secrete insulin, a prerequisite, there is still a beta cell synthesis and secretion of insulin function; Through the increase insulin 
levels for the liver or portal vein direct action, inhibit liver glycogen decomposition and glycogen vision, liver function was born generation and output glucose reduced; 3. Also may increase the organization for pancreatic insulin sensitiity and sugar (mainly through the use of possible receptors, therefore, the role) function is reduced fasting blood sugar and blood glucose after a meal. 
 
Application                                             
Acarbose is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is sold in Europe under the brand name Glucobay (Bayer AG), in North America as Precose 
(BayerPharmaceuticals), and in Canada as Prandase (Bayer AG). It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates.

 

 

 
Advantages:
 
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.


4. Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

Glibenclamide UPS Pharmaceutical Powder CAS 10238-21-8 Glibenclamide

 

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