Animal Veterinary Medicine QUININE SULFATE Cas:804-63-7 CAS NO.804-63-7

QUININE SULFATE

Cas:804-63-7

MF:C40H50N4O8S

EINECS No.:212-359-2

Assay: 99%

Standard: CP

Package:25kg/drum

Appearance: White crystal powder

Usage:

Quinineis a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike quinine, is an anti-arrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.

Though it has been synthesized in the lab, quinine occurs naturally in the bark of the cinchona tree. The medicinal properties of the cinchona tree were originally discovered by the Quechua Indians of Peru and Bolivia; later, the Jesuits were the first to bring the cinchona to Europe.

Quinine was the first effective treatment for malaria caused by Plasmodium falciparum, appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, when other drugs replaced it that have less unpleasant side effects. Since then, many effective antimalarials have been introduced, although quinine is still used to treat the disease in certain critical circumstances, such as severe malaria, and in impoverished regions due to its low cost. Quinine is available with a prescription in the United States and over-the-counter, in very small quantities, in tonic water. Quinine is also used to treat lupus and arthritis. Quinine was also frequently prescribed in the U.S. as an "off-label" treatment for nocturnal leg cramps, but this has since been prohibited, in effect, by an FDA statement warning against the practice.[1]

Quinine is very sensitive to ultraviolet light (UV) and will fluoresce in direct sunlight, due toits highly conjugated resonance structure (see Quinoline).